PRAJMALIUM

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C23H33N2O2
Molecular Weight	369.5203
Optical Activity	UNSPECIFIED
Defined Stereocenters	10 / 10
E/Z Centers	0
Charge	1

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]12N(C)C3=C(C=CC=C3)[C@]14C[C@H]5[C@@H]([C@H]4O)[C@@]6([H])C[C@]2([H])[N@+]5(CCC)[C@H](O)[C@H]6CC

InChI

InChIKey=UAUHEPXILIZYCU-ALHOSYKFSA-N

InChI=1S/C23H33N2O2/c1-4-10-25-17-11-14(13(5-2)22(25)27)19-18(25)12-23(21(19)26)15-8-6-7-9-16(15)24(3)20(17)23/h6-9,13-14,17-22,26-27H,4-5,10-12H2,1-3H3/q+1/t13-,14-,17-,18-,19-,20-,21+,22+,23+,25-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C23H32N2O2
Molecular Weight	368.5124
Charge	0
Count

Stereochemistry	EPIMERIC
Additional Stereochemistry	No
Defined Stereocenters	8 / 10
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1694924 | https://www.ncbi.nlm.nih.gov/pubmed/6723753 | https://www.ncbi.nlm.nih.gov/pubmed/4029242

Neo-Gilurythmal (or prajmaline), an antiarrhythmic agent, which is used to treat angina pectoris, Wolff–Parkinson–White Syndrome and coronary artery disease. Neo-Gilurythmal found to be effective even in the case where other previously used antiarrhythmics were ineffective.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
sodium channel complex 2 Target ID: GO:0034706 Sources: https://www.ncbi.nlm.nih.gov/pubmed/2422563\|https://www.ncbi.nlm.nih.gov/pubmed/1886140\|https://www.ncbi.nlm.nih.gov/pubmed/2410054\|https://www.ncbi.nlm.nih.gov/pubmed/6249418	Blocker 537

PubMed

Title	Date	PubMed

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Other

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:18:40 GMT 2023` Edited by `admin` on `Fri Dec 15 16:18:40 GMT 2023`
Record UNII	75934UD4GJ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PRAJMALIUM

Common Name

English

Prajmalium [WHO-DD]

Common Name

English

AJMALANINE, 17,21-DIHYDROXY-4-PROPYL-, (17R,21.ALPHA.)-

Common Name

English

PRAJMALIUM CATION

Common Name

English

PRAJMALINE

Common Name

English

PRAJMALINE [MI]

Common Name

English

N-PROPYLAJMALINE

Common Name

English

PRAJMALIUM ION

Common Name

English

Classification Tree Code System Code

WHO-ATC

C01BA08