FALINTOLOL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Description
Sources: https://link.springer.com/chapter/10.1007/978-1-4757-2085-3_6 | https://www.ncbi.nlm.nih.gov/pubmed/6148422 | https://www.ncbi.nlm.nih.gov/pubmed/2903204

Fallntolol is a beta-adrenergic receptor antagonist. Falintolol does not produce any noteworthy side effects and is capable of being an effective beta-blocking agent in open-angle glaucoma therapy.

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
Synthesis and beta-adrenergic blocking activity of new aliphatic and alicyclic oxime ethers.	1984 Oct	6148422
Pharmacokinetics of falintolol II. Absorption, distribution and elimination from tissues and organs following ocular administration and intravenous injection of falintolol in albino rabbits.	1989 Dec	2576299

Substance Class	Mixture Created by `admin` on `Sat Dec 16 11:19:11 GMT 2023` Edited by `admin` on `Sat Dec 16 11:19:11 GMT 2023`
Record UNII	733BXR9780
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FALINTOLOL

Official Name

English

ETHANONE, 1-CYCLOPROPYL-, O-(3-((1,1-DIMETHYLETHYL)AMINO)-2-HYDROXYPROPYL)OXIME

Systematic Name

English

CYCLOPROPYL METHYL KETONE, (±)-(EZ)-O-(3-(TERT-BUTYLAMINO)-2-HYDROXYPROPYL)OXIME

Common Name

English

FALINTOLOL, (E/Z)-(±)-

Common Name

English

falintolol [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29576

Created by admin on Sat Dec 16 11:19:11 GMT 2023 , Edited by admin on Sat Dec 16 11:19:11 GMT 2023

Code System Code Type Description

CAS

88134-91-2

Created by admin on Sat Dec 16 11:19:11 GMT 2023 , Edited by admin on Sat Dec 16 11:19:11 GMT 2023

ALTERNATIVE

NCI_THESAURUS

C73016

Created by admin on Sat Dec 16 11:19:11 GMT 2023 , Edited by admin on Sat Dec 16 11:19:11 GMT 2023

PRIMARY

CAS

90581-63-8

Created by admin on Sat Dec 16 11:19:11 GMT 2023 , Edited by admin on Sat Dec 16 11:19:11 GMT 2023

PRIMARY

MESH

C045888

Created by admin on Sat Dec 16 11:19:11 GMT 2023 , Edited by admin on Sat Dec 16 11:19:11 GMT 2023

PRIMARY

ChEMBL

CHEMBL111103

Created by admin on Sat Dec 16 11:19:11 GMT 2023 , Edited by admin on Sat Dec 16 11:19:11 GMT 2023

PRIMARY

EPA CompTox

DTXSID301024755

Created by admin on Sat Dec 16 11:19:11 GMT 2023 , Edited by admin on Sat Dec 16 11:19:11 GMT 2023

PRIMARY

FDA UNII

733BXR9780

Created by admin on Sat Dec 16 11:19:11 GMT 2023 , Edited by admin on Sat Dec 16 11:19:11 GMT 2023

PRIMARY

INN

5598

Created by admin on Sat Dec 16 11:19:11 GMT 2023 , Edited by admin on Sat Dec 16 11:19:11 GMT 2023

PRIMARY

EVMPD

SUB07499MIG

Created by admin on Sat Dec 16 11:19:11 GMT 2023 , Edited by admin on Sat Dec 16 11:19:11 GMT 2023

PRIMARY

All of the following components must be present:


					82MXJ61S2D

FALINTOLOL, (Z)-


					L7NSQ961ZC

FALINTOLOL, (E)-

Related Record Type Details


					UFV4G163GE

FALINTOLOL, (S)-

ENANTIOMER -> RACEMATE


					Y4J7U984EL

FALINTOLOL, (R)-

ENANTIOMER -> RACEMATE


					8ZG1XG255D

FALINTOLOL OXALATE

SALT/SOLVATE -> PARENT

Related Record Type Details


					733BXR9780

ACTIVE MOIETY

Definition References