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Details

Stereochemistry ACHIRAL
Molecular Formula C21H35N2O3.Cl
Molecular Weight 398.967
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LAPYRIUM CHLORIDE

SMILES

[Cl-].CCCCCCCCCCCC(=O)OCCNC(=O)C[N+]1=CC=CC=C1

InChI

InChIKey=HPKFFZSXDWPVLX-UHFFFAOYSA-N
InChI=1S/C21H34N2O3.ClH/c1-2-3-4-5-6-7-8-9-11-14-21(25)26-18-15-22-20(24)19-23-16-12-10-13-17-23;/h10,12-13,16-17H,2-9,11,14-15,18-19H2,1H3;1H

HIDE SMILES / InChI
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C21H35N2O3
Molecular Weight 363.5142
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including https://www.drugs.com/international/lapyrium-chloride.html | https://www.ncbi.nlm.nih.gov/pubmed/22426733 | https://www.ncbi.nlm.nih.gov/pubmed/6713839

Lapyrium, or lapirium, as the chloride salt lapirium chloride (INN) or lapyrium chloride (USAN), is a cationic surfactant that is used in cosmetic personal care products as a biocide and antistatic agent. A 50% solution of Lapyrium Chloride produced slight to moderate erythema. Lapyrium is also used in waste-water treatment and corrosion inhibition formulations.

Originator

Approval Year

1964
102
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
Withdrawn
VIRAC REX

Approved Use

Unknown
Sourcing

Sourcing

Vendor/AggregatorIDURL
ABI Chem
AC1L2KT2
ABI Chem
AC1Q5PN8
AK Scientific
9475AB
Alfa Chemistry
ACM6272748
BLD Pharm
BD01272406
http://www.bldpharm.com/products/109260-82-4.html
BOC Sciences
6272-74-8
BioSynth
W-104962
BlocksMatrix Scientific
99527
Compound Cloud
22659
Compound Cloud
22660
Hairui
HR133019
NCI Plated 2007
33659
Norris Pharm
NSZB-A026155
Smolecule
S532490
http://www.smolecule.com/products/s532490
THE BioTek
bt-272552
https://www.thebiotek.com/product/inhibitors/bt-272552
Tetrahedron
TS69219
ZINC
ZINC000008214591
http://zinc15.docking.org/substances/ZINC000008214591
eMolecules
44690858
PubMed

PubMed

TitleDatePubMed
Scapular reactivity to contact irritants: application-time and area variations.
1984 Apr-Jun
Intraregional variation between contact irritant patch test sites.
1984 Feb
Lipases as catalysts in synthesis of fine chemicals.
2012
Patents

Patents

US2928772
2

Sample Use Guides

In Vivo Use Guide
Twenty-two diurnally active, fair-skinned, male volunteers were repeatedly patch tested with 10, 15 and 20% lapyrium chloride (LC) for 5 consecutive days.
Route of Administration: Topical
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 16 16:58:52 GMT 2023
Edited
by admin
on Sat Dec 16 16:58:52 GMT 2023
Record UNII
732T8851QH
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LAPYRIUM CHLORIDE
INCI   MI   ORANGE BOOK   USAN  
INCI   USAN  
Official Name English
1-[[(2-Hydroxyethyl)carbamoyl]methyl]pyridinium chloride laurate (ester)
Common Name English
LAPIRIUM CHLORIDE
INN   WHO-DD  
INN  
Official Name English
LAPYRIUM CHLORIDE COMPONENT OF VIRAC REX
Common Name English
Lapirium chloride [WHO-DD]
Common Name English
1-((2-DODECANOYLOXYETHYLCARBAMOYL)METHYL)PYRIDINIUM CHLORIDE
Systematic Name English
N-(LAUROYLCOLAMINOFORMYLMETHYL)PYRIDINIUM CHLORIDE
Common Name English
lapirium chloride [INN]
Common Name English
LAPYRIUM CHLORIDE [USAN]
Common Name English
LAPYRIUM CHLORIDE [MI]
Common Name English
NSC-33659
Code English
PYRIDINIUM, 1-(2-OXO-2-((2-((1-OXODODECYL)OXY)ETHYL)AMINO)ETHYL)-, CHLORIDE
Systematic Name English
E-607
Brand Name English
LAPYRIUM CHLORIDE [ORANGE BOOK]
Common Name English
LAPYRIUM CHLORIDE [INCI]
Common Name English
EMCOL E-607
Brand Name English
VIRAC REX COMPONENT LAPYRIUM CHLORIDE
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 69131
Created by admin on Sat Dec 16 16:58:52 GMT 2023 , Edited by admin on Sat Dec 16 16:58:52 GMT 2023
NCI_THESAURUS C28394
Created by admin on Sat Dec 16 16:58:52 GMT 2023 , Edited by admin on Sat Dec 16 16:58:52 GMT 2023
Code System Code Type Description
PUBCHEM
22659
Created by admin on Sat Dec 16 16:58:52 GMT 2023 , Edited by admin on Sat Dec 16 16:58:52 GMT 2023
PRIMARY
FDA UNII
732T8851QH
Created by admin on Sat Dec 16 16:58:52 GMT 2023 , Edited by admin on Sat Dec 16 16:58:52 GMT 2023
PRIMARY
ECHA (EC/EINECS)
228-464-1
Created by admin on Sat Dec 16 16:58:52 GMT 2023 , Edited by admin on Sat Dec 16 16:58:52 GMT 2023
PRIMARY
EVMPD
SUB08404MIG
Created by admin on Sat Dec 16 16:58:52 GMT 2023 , Edited by admin on Sat Dec 16 16:58:52 GMT 2023
PRIMARY
NSC
33659
Created by admin on Sat Dec 16 16:58:52 GMT 2023 , Edited by admin on Sat Dec 16 16:58:52 GMT 2023
PRIMARY
CAS
6272-74-8
Created by admin on Sat Dec 16 16:58:52 GMT 2023 , Edited by admin on Sat Dec 16 16:58:52 GMT 2023
PRIMARY
CAS
1341-07-7
Created by admin on Sat Dec 16 16:58:52 GMT 2023 , Edited by admin on Sat Dec 16 16:58:52 GMT 2023
SUPERSEDED
NCI_THESAURUS
C87262
Created by admin on Sat Dec 16 16:58:52 GMT 2023 , Edited by admin on Sat Dec 16 16:58:52 GMT 2023
PRIMARY
DRUG CENTRAL
3314
Created by admin on Sat Dec 16 16:58:52 GMT 2023 , Edited by admin on Sat Dec 16 16:58:52 GMT 2023
PRIMARY
MERCK INDEX
m6691
Created by admin on Sat Dec 16 16:58:52 GMT 2023 , Edited by admin on Sat Dec 16 16:58:52 GMT 2023
PRIMARY Merck Index
ChEMBL
CHEMBL1201786
Created by admin on Sat Dec 16 16:58:52 GMT 2023 , Edited by admin on Sat Dec 16 16:58:52 GMT 2023
PRIMARY
INN
3204
Created by admin on Sat Dec 16 16:58:52 GMT 2023 , Edited by admin on Sat Dec 16 16:58:52 GMT 2023
PRIMARY
SMS_ID
100000082576
Created by admin on Sat Dec 16 16:58:52 GMT 2023 , Edited by admin on Sat Dec 16 16:58:52 GMT 2023
PRIMARY
DRUG BANK
DBSALT002416
Created by admin on Sat Dec 16 16:58:52 GMT 2023 , Edited by admin on Sat Dec 16 16:58:52 GMT 2023
PRIMARY
EPA CompTox
DTXSID5042085
Created by admin on Sat Dec 16 16:58:52 GMT 2023 , Edited by admin on Sat Dec 16 16:58:52 GMT 2023
PRIMARY
Related Record Type Details
Structure of LAPYRIUM
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of LAPYRIUM
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