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Details

Stereochemistry RACEMIC
Molecular Formula C20H24ClNO2
Molecular Weight 345.863
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of METHOPHOLINE

SMILES

COC1=C(OC)C=C2C(CCC3=CC=C(Cl)C=C3)N(C)CCC2=C1

InChI

InChIKey=YBCPYHQFUMNOJG-UHFFFAOYSA-N
InChI=1S/C20H24ClNO2/c1-22-11-10-15-12-19(23-2)20(24-3)13-17(15)18(22)9-6-14-4-7-16(21)8-5-14/h4-5,7-8,12-13,18H,6,9-11H2,1-3H3

HIDE SMILES / InChI
Molecular Formula C20H24ClNO2
Molecular Weight 345.863
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

METHOPHOLINE, an isoquinoline derivative, is an opioid analgesic drug. Its (R)-enatiomer is approximately six times more potent than codeine, and (S)-enantiomer is inactive. METHOPHOLINE was withdrawn from the market for reasons of safety.

Approval Year

Unknown
149,124

PubMed

Substance Class Chemical
Record UNII
72L4ZT2W1P
Record Status Validated (UNII)
Record Version
NIH
NCATS
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