U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C10H15NO
Molecular Weight 165.2322
Optical Activity ( + )
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of EPHEDRINE, (+)-

SMILES

CN[C@H](C)[C@@H](O)C1=CC=CC=C1

InChI

InChIKey=KWGRBVOPPLSCSI-PSASIEDQSA-N
InChI=1S/C10H15NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,10-12H,1-2H3/t8-,10-/m1/s1

HIDE SMILES / InChI

Molecular Formula C10H15NO
Molecular Weight 165.2322
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Racephedrine in combination with theophylline, phenobarbital was used to treat bronchial asthma. However, its application was substituted more effective agent. In addition, FDA has reviewed the final monograph for over-the-counter bronchodilator drug products to add additional warnings and to revise the indications in the labeling of products containing racephedrine hydrochloride.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Unknown

Approved Use

Unknown
Cmax

Cmax

ValueDoseCo-administeredAnalytePopulation
79.4 ng/mL
22 mg single, oral
dose: 22 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
EPHEDRINE plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: UNKNOWN
food status: UNKNOWN
AUC

AUC

ValueDoseCo-administeredAnalytePopulation
751 ng × h/mL
22 mg single, oral
dose: 22 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
EPHEDRINE plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: UNKNOWN
food status: UNKNOWN
T1/2

T1/2

ValueDoseCo-administeredAnalytePopulation
6.75 h
22 mg single, oral
dose: 22 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
EPHEDRINE plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: UNKNOWN
food status: UNKNOWN
PubMed

PubMed

TitleDatePubMed
Labeling for bronchodilators to treat asthma; cold, cough, allergy, bronchodilator, and antiasthmatic drug products for over-the-counter human use. Final rule.
2011 Jul 26
Patents

Patents

Sample Use Guides

Unknown
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 16 10:29:34 GMT 2023
Edited
by admin
on Sat Dec 16 10:29:34 GMT 2023
Record UNII
72087NSY56
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
EPHEDRINE, (+)-
Common Name English
D-EPHEDRINE
Common Name English
L-(+)-EPHEDRINE
Common Name English
(+)-(1S,2R)-EPHEDRINE
Common Name English
(1S,2R)-(+)-EPHEDRINE
Common Name English
BENZENEMETHANOL, .ALPHA.-(1-(METHYLAMINO)ETHYL)-, (S-(R*,S*))-
Systematic Name English
Classification Tree Code System Code
CFR 21 CFR 119.1
Created by admin on Sat Dec 16 10:29:34 GMT 2023 , Edited by admin on Sat Dec 16 10:29:34 GMT 2023
Code System Code Type Description
CAS
321-98-2
Created by admin on Sat Dec 16 10:29:34 GMT 2023 , Edited by admin on Sat Dec 16 10:29:34 GMT 2023
PRIMARY
FDA UNII
72087NSY56
Created by admin on Sat Dec 16 10:29:34 GMT 2023 , Edited by admin on Sat Dec 16 10:29:34 GMT 2023
PRIMARY
ECHA (EC/EINECS)
206-293-3
Created by admin on Sat Dec 16 10:29:34 GMT 2023 , Edited by admin on Sat Dec 16 10:29:34 GMT 2023
PRIMARY
EPA CompTox
DTXSID20891194
Created by admin on Sat Dec 16 10:29:34 GMT 2023 , Edited by admin on Sat Dec 16 10:29:34 GMT 2023
PRIMARY
PUBCHEM
9457
Created by admin on Sat Dec 16 10:29:34 GMT 2023 , Edited by admin on Sat Dec 16 10:29:34 GMT 2023
PRIMARY
Related Record Type Details
DIASTEREOISOMER -> DIASTEREOISOMER