IODINE I-131 APAMISTAMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 22:34:10 GMT 2025` Edited by `admin` on `Tue Apr 01 22:34:10 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type	IGG1
Sequence Origin	MOUSE
Sequence Type	COMPLETE
Record UNII	71RR81V666
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

IODINE (131I) APAMISTAMAB

Preferred Name

English

IODINE I-131 APAMISTAMAB

Common Name

English

IODINE I 131 MONOCLONAL ANTIBODY BC8

Common Name

English

I 131 MOAB BC8

Code

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN CD45 ANTIGEN) (MUS MUSCULUS MONOCLONAL BC8 .GAMMA.1-CHAIN), DISULFIDE WITH MUS MUSCULUS MONOCLONAL BC8 .KAPPA.-CHAIN, DIMER, LABELED WITH IODINE-131

Common Name

English

IODINE I 131 APAMISTAMAB [USAN]

Common Name

English

APAMISTAMAB IODINE I-131

Common Name

English

I-131-BC8

Code

English

IOMABB

Code

English

IOMAB-B

Code

English

I-131 MOAB BC8

Code

English

iodine (¹³¹I) apamistamab [INN]

Common Name

English

IODINE I 131 APAMISTAMAB

Official Name

English

IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C (LEUKOCYTE COMMON ANTIGEN, EC=3.1.3.48, CD45 ANTIGEN)MUS MUSCULUS MONOCLONAL ANTIBODYCONJUGATED ON ~6 TYROSYL AMINOACIDS TO IODINE (131I).GAMMA.1 HEAVY CHAIN (1-445)

Common Name

English

MOAB, BC8, MURINE, IODINE-I-131 RADIOLABELED TO CD45

Common Name

English

Iodine (131I) apamistamab [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C129819

Created by admin on Tue Apr 01 22:34:10 GMT 2025 , Edited by admin on Tue Apr 01 22:34:10 GMT 2025

FDA ORPHAN DRUG

510615

Created by admin on Tue Apr 01 22:34:10 GMT 2025 , Edited by admin on Tue Apr 01 22:34:10 GMT 2025

NCI_THESAURUS

C1511

Created by admin on Tue Apr 01 22:34:10 GMT 2025 , Edited by admin on Tue Apr 01 22:34:10 GMT 2025

Code System Code Type Description

INN

10856

Created by admin on Tue Apr 01 22:34:10 GMT 2025 , Edited by admin on Tue Apr 01 22:34:10 GMT 2025

PRIMARY

NCI_THESAURUS

C2527

Created by admin on Tue Apr 01 22:34:10 GMT 2025 , Edited by admin on Tue Apr 01 22:34:10 GMT 2025

PRIMARY

SMS_ID

100000181369

Created by admin on Tue Apr 01 22:34:10 GMT 2025 , Edited by admin on Tue Apr 01 22:34:10 GMT 2025

PRIMARY

FDA UNII

71RR81V666

Created by admin on Tue Apr 01 22:34:10 GMT 2025 , Edited by admin on Tue Apr 01 22:34:10 GMT 2025

PRIMARY

USAN

HI-44

Created by admin on Tue Apr 01 22:34:10 GMT 2025 , Edited by admin on Tue Apr 01 22:34:10 GMT 2025

PRIMARY

CAS

2097132-02-8

Created by admin on Tue Apr 01 22:34:10 GMT 2025 , Edited by admin on Tue Apr 01 22:34:10 GMT 2025

PRIMARY

From	To
1_22	1_96
1_148	1_203
1_259	1_319
1_365	1_423
1_225	2_225
1_228	2_228
1_230	2_230
1_223	3_218
2_22	2_96
2_148	2_203
2_259	2_319
2_365	2_423
2_223	4_218
3_23	3_92
3_138	3_198
4_23	4_92
4_138	4_198

Glycosylation Link Type	Site
N	1_295
N	2_295

Related Record Type Details


					FOR10CZY15

RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C

TARGET->RADIOLIGAND

Amount:


					55NP7G3PGH

NON-LABELED -> LABELED

Amount:

Related Record Type Details


					71RR81V666

IODINE I-131 APAMISTAMAB

ACTIVE MOIETY

Comments:

immunomodulator, antineoplastic

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
RADIOLABEL		RESIDUE_SPECIFIC	Tyrosine	Amount:	IOTYROSINE I-131	Q1M94GA18P

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL