GUMOKIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 13:07:21 GMT 2025` Edited by `admin` on `Wed Apr 02 13:07:21 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	6YS6C7XEC8
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

GUMOKIMAB

Official Name

English

AK-111

Preferred Name

English

AK111

Code

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN INTERLEUKIN 17A) (HUMAN-MUS MUSCULUS MONOCLONAL AK111 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL AK111 .KAPPA.-CHAIN, DIMER

Common Name

English

Gumokimab [WHO-DD]

Common Name

English

gumokimab [INN]

Common Name

English

Code System Code Type Description

CAS

2428381-52-4

Created by admin on Wed Apr 02 13:07:21 GMT 2025 , Edited by admin on Wed Apr 02 13:07:21 GMT 2025

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NCI_THESAURUS

C184849

Created by admin on Wed Apr 02 13:07:21 GMT 2025 , Edited by admin on Wed Apr 02 13:07:21 GMT 2025

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FDA UNII

6YS6C7XEC8

Created by admin on Wed Apr 02 13:07:21 GMT 2025 , Edited by admin on Wed Apr 02 13:07:21 GMT 2025

PRIMARY

SMS_ID

300000039121

Created by admin on Wed Apr 02 13:07:21 GMT 2025 , Edited by admin on Wed Apr 02 13:07:21 GMT 2025

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INN

11808

Created by admin on Wed Apr 02 13:07:21 GMT 2025 , Edited by admin on Wed Apr 02 13:07:21 GMT 2025

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From	To
4_138	4_198
4_23	4_93
3_138	3_198
3_23	3_93
2_370	2_428
2_264	2_324
2_223	4_218
2_147	2_203
2_22	2_96
1_370	1_428
1_264	1_324
1_232	2_232
1_229	2_229
1_223	3_218
1_147	1_203
1_22	1_96

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_300
N	2_300

Related Record Type Details


					R44E6C7B6J

INTERLEUKIN-17A

TARGET->LIGAND

Amount:

Related Record Type Details


					6YS6C7XEC8

GUMOKIMAB

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_450] [2_450]	C-TERMINUS		Amount:	LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL