MOROXYDINE HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H13N5O.ClH
Molecular Weight	207.661
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.NC(=N)NC(=N)N1CCOCC1

InChI

InChIKey=FXYZDFSNBBOHTA-UHFFFAOYSA-N

InChI=1S/C6H13N5O.ClH/c7-5(8)10-6(9)11-1-3-12-4-2-11;/h1-4H2,(H5,7,8,9,10);1H

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C6H13N5O
Molecular Weight	171.2003
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/9868507 | https://www.ncbi.nlm.nih.gov/pubmed/26428870

Moroxydine is an antiviral drug discovered in the 1950’s which was shown to be active against DNA and RNA viruses. Moroxydine analogues are potent anti-hepatitis C virus (HCV) agents.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Viral infection 4 Sources: https://www.ncbi.nlm.nih.gov/pubmed/9868507	Primary		Approved 8429	VIRULEX FORTE Approved Use Unknown

PubMed

Title	Date	PubMed
Trisodium bis-{1-[iminio-(morpholino)meth-yl]guanidinium} bis-[hexa-hydrogen-hexa-molybdoaluminate(III)] chloride icosa-hydrate.	2008 Jul 26	21203050
Effect of N-[Imino(4-morpholyl)methyl]guanidine on the oxidative status in rats with toxic hepatitis.	2009 Oct	20396755
[The influense of guanidine derivatives on free radical oxidation intensity and aconitase activity at development of brain ischemia-reperfusion at rats].	2009 Sep-Oct	20017395

Patents

Sample Use Guides

In Vivo Use Guide

Daily dose ranges from 25 to 5600 mg.

Route of Administration: Other

In Vitro Use Guide

6.3 μg/mL Moroxydine suppresses apoptosis in grass carp reovirus (GCRV)-infected Ctenopharyngodon idella kidney (CIK) cells.

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:37:45 GMT 2023` Edited by `admin` on `Fri Dec 15 18:37:45 GMT 2023`
Record UNII	6Y9698W0XT
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MOROXYDINE HYDROCHLORIDE

Common Name

English

NSC-47838

Code

English

NSC-63755

Code

English

NSC-43840

Code

English

Moroxydine hydrochloride [WHO-DD]

Common Name

English

NSC-407204

Code

English

MOROXYDINE HYDROCHLORIDE [MI]

Common Name

English

NSC-52355

Code

English

Code System Code Type Description

NSC

63755