AZINTUXIZUMAB VEDOTIN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 21:26:13 GMT 2025` Edited by `admin` on `Mon Mar 31 21:26:13 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Type	COMPLETE
Record UNII	6XQ9TM3U2G
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

azintuxizumab vedotin [INN]

Preferred Name

English

AZINTUXIZUMAB VEDOTIN

Official Name

English

Azintuxizumab vedotin [WHO-DD]

Common Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN CD319 ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONAL PR-1471272 HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL PR-1471272 LIGHT CHAIN, DIMER, BIS(THIOETHER) WITH N-(((4-((N-(6-(3-MERCAPTO-2,5-DIOXO-1-PYRROLIDINYL)-1-OX

Systematic Name

English

ABBV-838

Common Name

English

Code System Code Type Description

INN

10499

Created by admin on Mon Mar 31 21:26:13 GMT 2025 , Edited by admin on Mon Mar 31 21:26:13 GMT 2025

PRIMARY

SMS_ID

300000025294

Created by admin on Mon Mar 31 21:26:13 GMT 2025 , Edited by admin on Mon Mar 31 21:26:13 GMT 2025

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DRUG BANK

DB14847

Created by admin on Mon Mar 31 21:26:13 GMT 2025 , Edited by admin on Mon Mar 31 21:26:13 GMT 2025

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FDA UNII

6XQ9TM3U2G

Created by admin on Mon Mar 31 21:26:13 GMT 2025 , Edited by admin on Mon Mar 31 21:26:13 GMT 2025

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CAS

1826819-58-2

Created by admin on Mon Mar 31 21:26:13 GMT 2025 , Edited by admin on Mon Mar 31 21:26:13 GMT 2025

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NCI_THESAURUS

C122816

Created by admin on Mon Mar 31 21:26:13 GMT 2025 , Edited by admin on Mon Mar 31 21:26:13 GMT 2025

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From	To
1_22	1_96
1_144	1_200
1_220	3_220
1_226	2_226
1_229	2_229
1_261	1_321
2_367	2_425
2_22	2_96
2_144	2_200
2_220	4_220
2_261	2_321
2_367	2_425
3_23	3_93
3_140	3_200
4_23	4_93
4_140	4_200

Glycosylation Link Type	Site
N	1_297
N	2_297

Related Record Type Details


					0KAU401ANQ

SLAM FAMILY MEMBER 7

TARGET->CONJUGATED TOXIN

Amount:


					Q3606FDE0B

VEDOTIN FRAGMENT

TOXIN -> CONJUGATE

Related Record Type Details


					6XQ9TM3U2G

AZINTUXIZUMAB VEDOTIN

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_220] [1_226] [1_229] [2_220] [2_226] [2_229] [3_220] [4_220]		C	Amount:	Cysteinyl vedotin	6603L01WUR

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL