ASB-16165

Details

Stereochemistry	ACHIRAL
Molecular Formula	C23H29N5O2S
Molecular Weight	439.574
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=NN(C2CCCCC2)C3=C1C=C(S3)C(=O)NC4=CC=C(N=C4)N5CCC(O)CC5

InChI

InChIKey=NFWMSIMJLJHZPQ-UHFFFAOYSA-N

InChI=1S/C23H29N5O2S/c1-15-19-13-20(31-23(19)28(26-15)17-5-3-2-4-6-17)22(30)25-16-7-8-21(24-14-16)27-11-9-18(29)10-12-27/h7-8,13-14,17-18,29H,2-6,9-12H2,1H3,(H,25,30)

HIDE SMILES / InChI

Molecular Formula	C23H29N5O2S
Molecular Weight	439.574
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Phosphodiesterase 7A inhibitor ASB16165 impairs proliferation of keratinocytes in vitro and in vivo.	2010-05-10	20132810
ASB16165, a phosphodiesterase 7A inhibitor, reduces cutaneous TNF-alpha level and ameliorates skin edema in phorbol ester 12-O-tetradecanoylphorbol-13-acetate-induced skin inflammation model in mice.	2009-06-24	19379723
Effect of phosphodiesterase 7 inhibitor ASB16165 on development and function of cytotoxic T lymphocyte.	2009-01	18992850
Phosphodiesterase 7A inhibitor ASB16165 suppresses proliferation and cytokine production of NKT cells.	2009	19477436

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 23:00:40 GMT 2025` Edited by `admin` on `Mon Mar 31 23:00:40 GMT 2025`
Record UNII	6X97K9I3QN
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ASB-16165

Common Name

English

1H-THIENO(2,3-C)PYRAZOLE-5-CARBOXAMIDE, 1-CYCLOHEXYL-N-(6-(4-HYDROXY-1-PIPERIDINYL)-3-PYRIDINYL)-3-METHYL-

Preferred Name

English

Code System Code Type Description

CAS

873541-45-8

Created by admin on Mon Mar 31 23:00:40 GMT 2025 , Edited by admin on Mon Mar 31 23:00:40 GMT 2025

PRIMARY

PUBCHEM

25255436

Created by admin on Mon Mar 31 23:00:40 GMT 2025 , Edited by admin on Mon Mar 31 23:00:40 GMT 2025

PRIMARY

FDA UNII

6X97K9I3QN

Created by admin on Mon Mar 31 23:00:40 GMT 2025 , Edited by admin on Mon Mar 31 23:00:40 GMT 2025

PRIMARY

Related Record Type Details


					6X97K9I3QN

ASB-16165

ACTIVE MOIETY