REVOSPIRONE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C18H21N5O3S
Molecular Weight	387.456
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O=C1N(CCCN2CCN(CC2)C3=NC=CC=N3)S(=O)(=O)C4=CC=CC=C14

InChI

InChIKey=MPLTZRTXQLNGED-UHFFFAOYSA-N

InChI=1S/C18H21N5O3S/c24-17-15-5-1-2-6-16(15)27(25,26)23(17)10-4-9-21-11-13-22(14-12-21)18-19-7-3-8-20-18/h1-3,5-8H,4,9-14H2

HIDE SMILES / InChI

Molecular Formula	C18H21N5O3S
Molecular Weight	387.456
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2149168

Revospirone (BAY VQ 7813) is a pyrimidinylpiperazine derivative that acts as partial agonist at 5-HT1A receptors. Head shakes were reported after administration of revospirone in pigs, and once daily administration for 3-5 days led to a reduction in this head shake response. No behavioral alterations were observed. This compound was never marketed

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
5-hydroxytryptamine receptor 1A 54 Target ID: P08908 Gene ID: 3350.0 Gene Symbol: HTR1A Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/2149168	Partial Agonist 290

Substance Class	Chemical Created by `admin` on `Sat Dec 16 15:55:50 GMT 2023` Edited by `admin` on `Sat Dec 16 15:55:50 GMT 2023`
Record UNII	6X8764TW2J
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

REVOSPIRONE

Official Name

English

revospirone [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C28197