Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C2H7NO.FH |
| Molecular Weight | 81.0894 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
F.NCCO
InChI
InChIKey=PTOKDFKDUYQOAK-UHFFFAOYSA-N
InChI=1S/C2H7NO.FH/c3-1-2-4;/h4H,1-3H2;1H
| Molecular Formula | C2H7NO |
| Molecular Weight | 61.0831 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | FH |
| Molecular Weight | 20.0063 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Monoethanolamine is both a primary amine and a primary alcohol. It is an olamine derivative. Monoethanolamine occurs in every cell in the human body as the head group of Phosphatidylethanolamine. Monoethanolamine is a component of glycosylphosphatidylinositol-anchored proteins, which are essential for viability. Other sources of monoethanolamine or phosphoethanolamine in the human body are the degradation of sphingosine phosphate by sphingosine phosphate lyase and the degradation of the endocannabinoid anandamide by the fatty acid amine hydrolase. Monoethanolamine stimulates the rapid growth of mammalian cells in culture. Monoethanolamine has a cardioprotective role against ischemia/reperfusion injury via activation of the transcription factor STAT-3. Monoethanolamine is a chemical intermediate in the manufacture of cosmetics, surface-active agents, emulsifiers, pharmaceuticals, and plasticizing agents.
Originator
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Chlorpromazine-induced increase in dipalmitoylphosphatidylserine surface area in monolayers at room temperature. | 2001 Apr 1 |
|
| Structure-activity relationship studies of (+/-)-terbutaline and (+/-)-fenoterol on beta3-adrenoceptors in the guinea pig gastric fundus. | 2001 Aug |
|
| Ethanolamine transport in human placental brush-border membrane vesicles. | 2001 Aug |
|
| Determination of aliphatic side-chain conformation using cross-correlated relaxation: application to an extraordinarily stable 2'-aminoethoxy-modified oligonucleotide triplex. | 2001 Aug 1 |
|
| Liquid ionization mass spectrometry of some triorganotin carboxylates. | 2001 Dec |
|
| Beta 3 agonists. Part 1: evolution from inception to BMS-194449. | 2001 Dec 3 |
|
| Protein kinase C activation by 12-0-tetradecanoylphorbol 13-acetate in CG-4 line oligodendrocytes stimulates turnover of choline and ethanolamine phospholipids by phospholipase D and induces rapid process contraction. | 2001 Jan |
|
| 5'-Deoxyadenosine contacts the substrate radical intermediate in the active site of ethanolamine ammonia-lyase: 2H and 13C electron nuclear double resonance studies. | 2001 Jan 9 |
|
| Synthesis of a chiral aziridine derivative as a versatile intermediate for HIV protease inhibitors. | 2001 Jul 26 |
|
| Preparation of potent cytotoxic ribonucleases by cationization: enhanced cellular uptake and decreased interaction with ribonuclease inhibitor by chemical modification of carboxyl groups. | 2001 Jun 26 |
|
| Resveratrol inhibits the formation of phosphatidic acid and diglyceride in chemotactic peptide- or phorbol ester-stimulated human neutrophils. | 2001 Mar |
|
| trans-Bis(ethanolamine-N,O)bis(saccharinato-N)copper(II). | 2001 Mar |
|
| Development of an electrochemical immunosensor for direct detection of interferon-gamma at the attomolar level. | 2001 Mar 1 |
|
| Structure and expression of the murine phosphatidylserine synthase-1 gene. | 2001 Mar 16 |
|
| Transport characteristics of peptides and peptidomimetics: II. Hydroxyethylamine bioisostere-containing peptidomimetics as substrates for the oligopeptide transporter and P-glycoprotein in the intestinal mucosa. | 2001 May |
|
| Nature of glycosylphosphatidylinositols produced by mouse embryonic stem cells. | 2001 Nov |
|
| Luminol chemiluminescence in unbuffered solutions with a cobalt(II)-ethanolamine complex immobilized on resin as catalyst and its application to analysis. | 2001 Nov 1 |
|
| Reductive demercuration in deprotection of trityl thioethers, trityl amines, and trityl ethers. | 2001 Nov 16 |
|
| Tissue-specific and developmental effects of the easily shocked mutation on ethanolamine kinase activity and phospholipid composition in Drosophila melanogaster. | 2001 Oct |
|
| Poly(amide ester)s from 2,6-pyridinedicarboxylic acid and ethanolamine derivatives: identification of macrocycles by matrix-assisted laser desorption/ionization mass spectrometry. | 2002 |
|
| [Structural and metabolic status and functional properties of erythrocytes in schizophrenic patients]. | 2002 |
|
| Glycosylphosphatidylinositol (GPI)-anchored proteins. | 2002 Apr |
|
| Mutations inducing divergent shifts of constitutive activity reveal different modes of binding among catecholamine analogues to the beta(2)-adrenergic receptor. | 2002 Apr |
|
| Endoscopic management and long-term follow-up of Dieulafoy's lesions in the upper GI tract. | 2002 Apr |
|
| Amiodarone-induced phospholipidosis: an in vivo [14C]-acetate uptake study in rat. | 2002 Aug |
|
| Algicidal effectiveness of Clearigate, Cutrine-Plus, and copper sulfate and margins of safety associated with their use. | 2002 Jul |
|
| Comparative study of the effects of short- and long-term ethanol treatment and alcohol withdrawal on phospholipid biosynthesis in rat hepatocytes. | 2002 Mar |
|
| Behavior and characteristics of amine derivatives obtained with o-phthaldialdehyde/3-mercaptopropionic acid and with o-phthaldialdehyde/N-acetyl-L-cysteine reagents. | 2002 Mar 8 |
|
| Endometriosis in reproductive immunology. | 2002 May |
|
| Phospholipid biosynthesis in the oyster protozoan parasite, Perkinsus marinus. | 2002 May |
Sample Use Guides
In Vivo Use Guide
Curator's Comment: Ethanolamine is a product of metabolism of sphingosine-1-phosphate (of S1P)
Rat: single injection 5 mg/kg of S1P
Route of Administration:
Intravenous
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:36:00 UTC 2023
by
admin
on
Fri Dec 15 15:36:00 UTC 2023
|
| Record UNII |
6UT951O512
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Systematic Name | English | ||
|
Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
DTXSID10169091
Created by
admin on Fri Dec 15 15:36:00 UTC 2023 , Edited by admin on Fri Dec 15 15:36:00 UTC 2023
|
PRIMARY | |||
|
17140-77-1
Created by
admin on Fri Dec 15 15:36:00 UTC 2023 , Edited by admin on Fri Dec 15 15:36:00 UTC 2023
|
PRIMARY | |||
|
22617393
Created by
admin on Fri Dec 15 15:36:00 UTC 2023 , Edited by admin on Fri Dec 15 15:36:00 UTC 2023
|
PRIMARY | |||
|
6UT951O512
Created by
admin on Fri Dec 15 15:36:00 UTC 2023 , Edited by admin on Fri Dec 15 15:36:00 UTC 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
PARENT -> SALT/SOLVATE | |||
|
|
PARENT -> SALT/SOLVATE |
