LALIKINOGENE SIFUPLASMID

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Sat Dec 16 18:19:54 GMT 2023` Edited by `admin` on `Sat Dec 16 18:19:54 GMT 2023`
Nucleic Acid Type	PLASMID
Nucleic Acid Subtype
Sequence Type	COMPLETE
Record UNII	6TH2K6V2RW
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

LALIKINOGENE SIFUPLASMID

Official Name

English

lalikinogene sifuplasmid [INN]

Common Name

English

DNA (RECOMBINANT PLASMID VECTOR PGX6010 HUMAN CYTOMEGALOVIRUS PROMOTER PLUS HUMAN INTERLEUKIN 12 SUBUNIT .BETA. CODON-OPTIMIZED GENE IL-12B PLUS SV40 POLYADENYLATION SIGNAL PLUS SIMIAN CYTOMEGALOVIRUS PROMOTER PLUS HUMAN INTERLEUKIN 12 SUBUNIT .ALPHA. CO

Common Name

English

DNA PLASMID ENCODING CODON-OPTIMIZED HUMAN INTERLEUKIN 12 SUBUNIT ALPHA (IL12A, IL-12 SUBUNIT P35) AND SUBUNIT BETA (IL12B, IL-12 SUBUNIT P40), EXPRESSION OF THE IL-12 SUBUNIT P35 IS DRIVEN BY THE SIMIAN CYTOMEGALOVIRUS (SCMV) PROMOTOR AND TERMINATED WIT

Common Name

English

Code System Code Type Description

FDA UNII

6TH2K6V2RW

Created by admin on Sat Dec 16 18:19:54 GMT 2023 , Edited by admin on Sat Dec 16 18:19:54 GMT 2023

PRIMARY

NCI_THESAURUS

C184856

Created by admin on Sat Dec 16 18:19:54 GMT 2023 , Edited by admin on Sat Dec 16 18:19:54 GMT 2023

PRIMARY

INN

11790

Created by admin on Sat Dec 16 18:19:54 GMT 2023 , Edited by admin on Sat Dec 16 18:19:54 GMT 2023

PRIMARY

CAS

2418030-84-7

Created by admin on Sat Dec 16 18:19:54 GMT 2023 , Edited by admin on Sat Dec 16 18:19:54 GMT 2023

PRIMARY

Sugar	Site Range	Site Count
Deoxyribose (DNA)	1_1-1_6229	6229 / 6229

Linkage	Site Range	Site Count
Phosphate	1_2-1_6229	6228 / 6228

Related Record Type Details


					6TH2K6V2RW

LALIKINOGENE SIFUPLASMID

ACTIVE MOIETY

Comments:

IL-12 is a pro-inflammatory cytokine that regulates cell-mediated immune responses via a wide array of mechanisms

Amount: