U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

2011
587
Substance Class Protein
Created
by admin
on Wed Apr 02 07:04:53 GMT 2025
Edited
by admin
on Wed Apr 02 07:04:53 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
6T8C155666
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
IPILIMUMAB
DASH   EMA EPAR   INN   MART.   MI   USAN   VANDF   WHO-DD  
USAN   INN  
Official Name English
YERVOY
Preferred Name English
ipilimumab [INN]
Common Name English
MDX-101
Code English
IPILIMUMAB [USAN]
Common Name English
BMS-734016
Code English
MDX010
Code English
IPILIMUMAB [EMA EPAR]
Common Name English
IPILIMUMAB [MI]
Common Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN CTLA-4 (ANTIGEN)) (HUMAN .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN .KAPPA.-CHAIN, DIMER
Common Name English
IPILIMUMAB [PURPLE BOOK CDER]
Common Name English
IPILIMUMAB [MART.]
Common Name English
MDX-CTLA-4
Code English
IMMUNOGLOBULIN G1, ANTI-(HUMAN CTLA-4 (ANTIGEN)) (HUMAN .GAMMA.1-CHAIN), DISULPHIDE WITH HUMAN .KAPPA.-CHAIN, DIMER
Common Name English
IPILIMUMAB [VANDF]
Common Name English
Ipilimumab [WHO-DD]
Common Name English
IPILIMUMAB [JAN]
Common Name English
BMS734016
Code English
MDX-010
Code English
Classification Tree Code System Code
FDA ORPHAN DRUG 595917
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
FDA ORPHAN DRUG 177703
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
EMA ASSESSMENT REPORTS YERVOY (AUTHORIZED: MELANOMA)
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
NCI_THESAURUS C129822
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
WHO-VATC QL01XC11
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
FDA ORPHAN DRUG 657418
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
FDA ORPHAN DRUG 445014
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
LIVERTOX NBK548335
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
NDF-RT N0000182635
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
NCI_THESAURUS C128036
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
FDA ORPHAN DRUG 545116
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
WHO-ATC L01XC11
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
FDA ORPHAN DRUG 317710
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
Code System Code Type Description
DRUG CENTRAL
4958
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
PRIMARY
JAPANESE REVIEW
YERVOY
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
PRIMARY APPROVE JULY 2015
INN
8568
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
PRIMARY
MESH
C508317
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
PRIMARY
DRUG BANK
DB06186
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
PRIMARY
NDF-RT
N0000182157
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
PRIMARY Increased T Lymphocyte Activation [PE]
MERCK INDEX
m6384
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
PRIMARY Merck Index
DAILYMED
6T8C155666
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
PRIMARY
LACTMED
Ipilimumab
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
PRIMARY
WIKIPEDIA
IPILIMUMAB
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
PRIMARY
IUPHAR
6888
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
PRIMARY
NDF-RT
N0000182634
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
PRIMARY CTLA-4-directed Antibody Interactions [MoA]
SMS_ID
100000092960
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
PRIMARY
EVMPD
SUB29397
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
PRIMARY
RXCUI
1094833
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
PRIMARY RxNorm
ChEMBL
CHEMBL1789844
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
PRIMARY
FDA UNII
6T8C155666
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
PRIMARY
NCI_THESAURUS
C2654
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
PRIMARY
CAS
477202-00-9
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
PRIMARY
USAN
QQ-65
Created by admin on Wed Apr 02 07:04:53 GMT 2025 , Edited by admin on Wed Apr 02 07:04:53 GMT 2025
PRIMARY
From To
1_22 1_96
1_145 1_201
1_221 3_215
1_227 2_227
1_230 2_230
1_262 1_322
1_368 1_426
2_22 2_96
2_145 2_201
2_221 4_215
2_262 2_322
2_368 2_426
3_23 3_89
3_135 3_195
4_23 4_89
4_135 4_195
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_298
N 2_298
Related Record Type Details
CYTOTOXIC T-LYMPHOCYTE PROTEIN 4
TARGET -> INHIBITOR
ACTIVATOR
Related Record Type Details
IPILIMUMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:APPROXIMATE CHEMICAL
NIH
NCATS
PRIVACY NOTICE
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966