Ingitamig

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 13:44:04 GMT 2025` Edited by `admin` on `Wed Apr 02 13:44:04 GMT 2025`
Protein Type	TRISPECIFIC ANTIBODY
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	6R6GWJ8GDZ
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Ingitamig

Official Name

English

BMS-986392

Preferred Name

English

CC-92328

Code

English

INGITAMIG [USAN]

Common Name

English

DF3001

Code

English

Immunoglobulin G1 [de-446-lysine], bispecific, anti-(human tumor necrosis factor receptor superfamily protein TNFRSF17) (human clone EEcpSTF2cp165-cp14 ?1-chain) fusion protein with peptide linker (SGSGGGGS) fusion protein immunoglobulin anti-(human kill

Common Name

English

DF-3001

Code

English

Code System Code Type Description

CAS

2839572-09-5

Created by admin on Wed Apr 02 13:44:04 GMT 2025 , Edited by admin on Wed Apr 02 13:44:04 GMT 2025

PRIMARY

NCI_THESAURUS

C190202

Created by admin on Wed Apr 02 13:44:04 GMT 2025 , Edited by admin on Wed Apr 02 13:44:04 GMT 2025

PRIMARY

SMS_ID

300000032865

Created by admin on Wed Apr 02 13:44:04 GMT 2025 , Edited by admin on Wed Apr 02 13:44:04 GMT 2025

PRIMARY

FDA UNII

6R6GWJ8GDZ

Created by admin on Wed Apr 02 13:44:04 GMT 2025 , Edited by admin on Wed Apr 02 13:44:04 GMT 2025

PRIMARY

INN

12958

Created by admin on Wed Apr 02 13:44:04 GMT 2025 , Edited by admin on Wed Apr 02 13:44:04 GMT 2025

PRIMARY

USAN

LM-96

Created by admin on Wed Apr 02 13:44:04 GMT 2025 , Edited by admin on Wed Apr 02 13:44:04 GMT 2025

PRIMARY

From	To
4_136	4_196
4_23	4_89
3_136	3_196
3_23	3_89
2_366	2_424
2_260	2_320
2_219	4_216
1_219	3_216
2_143	2_199
2_22	2_96
1_602	1_676
1_553	1_624
1_476	1_541
1_366	1_424
1_353	2_348
1_260	1_320
1_228	2_228
1_225	2_225
1_143	1_199
1_22	1_96

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_296
N	2_296

Related Record Type Details


					6R6GWJ8GDZ

Ingitamig

ACTIVE MOIETY

Comments:

CC-92328 is designed to bind to BCMA expressed on MM cells to localize immune responses to the tumor microenvironment and to stabilize BCMA on the cell surface. When bound to MM cells, CC-92328 can concurrently bind to CD16a and NKG2D on effector cells (primarily NK cells), thus potentiating NK cell mediated killing of malignant cells and promoting the release of cytokines

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL