| Stereochemistry | ABSOLUTE |
| Molecular Formula | C24H26O13 |
| Molecular Weight | 522.4554 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 5 / 5 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=C(OC)C(O)=CC(=C1)C2=COC3=C(C2=O)C(O)=C(OC)C(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)=C3
InChI
InChIKey=LNQCUTNLHUQZLR-OZJWLQQPSA-N
InChI=1S/C24H26O13/c1-32-13-5-9(4-11(26)22(13)33-2)10-8-35-12-6-14(23(34-3)19(29)16(12)17(10)27)36-24-21(31)20(30)18(28)15(7-25)37-24/h4-6,8,15,18,20-21,24-26,28-31H,7H2,1-3H3/t15-,18-,20+,21-,24-/m1/s1
| Molecular Formula | C24H26O13 |
| Molecular Weight | 522.4554 |
| Charge | 0 |
| Count |
MOL RATIO
1 MOL RATIO (average) |
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 5 / 5 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
idin is an isoflavone, isolated from several species of irises like orris root, Iris florentina or Iris versicolor, also commonly known as the larger blue flag. Iridin in smaller doses can be used as diuretic and cholagogue agent. Iridin is toxic and these plants have been mentioned as causing poisoning in humans and animals.
Originator
Approval Year
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
PubMed
Patents
Sample Use Guides
Five grains of iridin, mixed with a little bile and water, and placed in the duodenum, very powerfully stimulate the liver
Route of Administration:
Oral
MCF-7 and T47D human breast cancer cells were used for activity evaluation. Cells were seeded into 96-well tissue culture plates in 5% DCC-treated, FBS-supplemented RPMI phenol red-free medium at a density of 1 x 10^4 cells/well. Test compounds were added in DMSO solution (control contained 1% DMSO) and incubated at 37 °C with 5% CO2 for 96 h. In all experiments, serial dilutions of estradiol were added as a positive control. To evaluate relative cell concentrations, Alamar Blue reagent was used. After 3 h, fluorescence was measured at 590 nm with excitation at 530 nm using a FL500 spectrophotometer
