U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C4H10
Molecular Weight 58.1222
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BUTANE

SMILES

CCCC

InChI

InChIKey=IJDNQMDRQITEOD-UHFFFAOYSA-N
InChI=1S/C4H10/c1-3-4-2/h3-4H2,1-2H3

HIDE SMILES / InChI

Molecular Formula C4H10
Molecular Weight 58.1222
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Butane is gaseous alkane with four carbon atoms. Normal butane can be used for gasoline blending, as a fuel gas, fragrance extraction solvent, either alone or in a mixture with propane, and as a feedstock for the manufacture of ethylene and butadiene, a key ingredient of synthetic rubber. Butane is known to be a suffocating gas with a narcotic action. Inhalation of butane can cause euphoria, drowsiness, unconsciousness, asphyxia, cardiac arrhythmia, fluctuations in blood pressure and temporary memory loss, when abused directly from a highly pressurized container, and can result in death from asphyxiation and ventricular fibrillation. Abuse is frequent because butane is easily available and its sale is not restricted. Cases of sudden death in teenagers have been increasing since the 1980s , and over the past few years, there have been an increasing number of publications on the subject.

Approval Year

PubMed

PubMed

TitleDatePubMed
The influence of model drugs on the preparation of pellets by extrusion/spheronization: II. Spheronization parameters.
2002-01-01
Ab initio study of the structures and stabilities of the dimer of ethyl cation, (C(2)H(+)(5))(2) and related C(4)H(10)(2+) isomers.
2001-12-28
Computation and mutagenesis suggest a right-handed structure for the synaptobrevin transmembrane dimer.
2001-12-01
Antibacterial effect of parabens against planktonic and biofilm Streptococcus sobrinus.
2001-12
Induction of histone acetylation in rat liver and hepatoma by organosulfur compounds including diallyl disulfide.
2001-11-29
Reactivity of mono-meso-substituted iron(II) octaethylporphyrin complexes with hydrogen peroxide in the absence of dioxygen. Evidence for nucleophilic attack on the heme.
2001-11-28
Novel approaches to polynuclear platinum pro-drugs. Selective release of cytotoxic platinum-spermidine species through hydrolytic cleavage of carbamates.
2001-11-19
Transformation of mutagenic aromatic amines into non-mutagenic species by alkyl substituents. Part I. Alkylation ortho to the amino function.
2001-11-15
Triplet excitation transfer through the walls of hemicarcerands: dependence of the electronic coupling on the size of the molecular cage.
2001-11-07
Glucosinolate content and isothiocyanate evolution--two measures of the biofumigation potential of plants.
2001-11
Domestic aerosol and flash fire: warning from a fatal case.
2001-11
Alterations of beta- and gamma-catenin in N-butyl-N-(-4-hydroxybutyl)nitrosamine-induced murine bladder cancer.
2001-10-01
Cathinone (Khat) and methcathinone (CAT) in urine specimens: a gas chromatographic-mass spectrometric detection procedure.
2001-10
Crystal structure of Staphylococcus aureus tyrosyl-tRNA synthetase in complex with a class of potent and specific inhibitors.
2001-10
Pharmacokinetics of salicylate ester prodrugs of cyclic HPMPC in dogs.
2001-09-21
Human physiologic factors in respiratory uptake of 1,3-butadiene.
2001-09
An ESR and HPLC-EC assay for the detection of alkyl radicals.
2001-09
A novel gene encoding a 54 kDa polypeptide is essential for butane utilization by Pseudomonas sp. IMT37.
2001-09
[(Dihydroindenyl)oxy]alkonic acid inhibits the cystic fibrosis transmembrane conductance regulator.
2001-08-31
Methylated analogues of methyl (R)-4-(3,4-dichlorophenylacetyl)- 3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate (GR-89,696) as highly potent kappa-receptor agonists: stereoselective synthesis, opioid-receptor affinity, receptor selectivity, and functional studies.
2001-08-16
Microcalorimetric studies on the interaction mechanism between proteins and hydrophobic solid surfaces in hydrophobic interaction chromatography: effects of salts, hydrophobicity of the sorbent, and structure of the protein.
2001-08-15
Protein analysis by capillary zone electrophoresis utilizing a trifunctional diamine for silica coating.
2001-08-15
Influence of structural variation in room-temperature ionic liquids on the selectivity and efficiency of competitive alkali metal salt extraction by a crown ether.
2001-08-01
Sorption and desorption behavior of organotin compounds in sediment-pore water systems.
2001-08-01
Investigation of the mechanism of alkane reductive elimination and skeletal isomerization in Tp'Rh(CNneopentyl)(R)H complexes: the role of alkane complexes.
2001-08-01
Simultaneous determination of butyltin and phenyltin species in sediments using ultrasound-assisted leaching.
2001-08
Effects of mono-n-butyl phthalate on the development of rat embryos: in vivo and in vitro observations.
2001-08
Endovascular treatment of a lenticulostriate artery aneurysm with N-butyl cyanoacrylate.
2001-08
Nonhalogenated alkane anesthetics fail to potentiate agonist actions on two ligand-gated ion channels.
2001-08
NMR imaging of mass transport and related phenomena in porous catalysts and sorbents.
2001-07-11
A calorimetric study of the binding of S-alkylglutathiones to glutathione S-transferase.
2001-07-09
NEXAFS study of 1-butanethiol adsorbed on Cu(111) and square root of 7 x square root of 7 R19.1 degrees S/Cu(111).
2001-07-01
Analysis of stable low molecular weight (LMW) RNA profiles of hydrocarbon metabolizing bacteria by staircase electrophoresis.
2001-07
Induction of butane consumption in Pseudomonas butanovora.
2001-07
The use of 3M porous polymer extraction discs in assessing protective clothing chemical permeation.
2001-07
Headspace/solid-phase microextraction/gas chromatography-mass spectrometry: a screening technique for the recovery and identification of volatile organic compounds (VOC's) in postmortem blood and viscera samples.
2001-07
Membrane interactions of a new class of anticancer agents derived from arylchloroethylurea: a FTIR spectroscopic study.
2001-06
Probing molecular conformations with electron momentum spectroscopy: the case of n-butane.
2001-05-02
Dimeric phenalenyl-based neutral radical molecular conductors.
2001-05-02
Manganese, iron and sulfur K edge XAFS of promoted sulfated zirconia catalysts.
2001-03-01
Alkyl ester prodrugs for improved topical delivery of ibuprofen.
2001-03
Hydrogenolysis of cyclohexane over Ir/SiO(2) catalyst: a mechanistic study of carbon--carbon bond cleavage on metallic surfaces.
2001-02-28
Conformationally restricted analogues of 1N,14N-bisethylhomospermine (BE-4-4-4): synthesis and growth inhibitory effects on human prostate cancer cells.
2001-02-01
Ethyl side-chain modifications in novel flexible antiestrogens--design, synthesis and biological efficacy in assay against the MCF-7 breast tumor cell line.
2001-02
Proposal for a method for testing resistance of clothing and gloves to penetration by pesticides.
2001
Molecular and cellular fundamentals of aerobic cometabolism of trichloroethylene.
2001
A biological loss of endosulfan and related chlorinated organic compounds from aqueous systems in the presence and absence of oxygen.
2001
Bioaugmentation of butane-utilizing microorganisms to promote cometabolism of 1,1,1-trichloroethane in groundwater microcosms.
2001
Partial pressures and nature of products. Application to the photolysis of PH3 and NH3 in the atmosphere of Jupiter and Saturn.
2001
[Microcirculation in patients with viral hepatitis B taking ephedrone].
2001
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:07:55 GMT 2025
Edited
by admin
on Mon Mar 31 18:07:55 GMT 2025
Record UNII
6LV4FOR43R
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BUTANE
FCC   HSDB   II   INCI   MART.   MI   WHO-DD  
INCI  
Official Name English
E-943
Preferred Name English
BUTANE [HSDB]
Common Name English
BUTANE [MI]
Common Name English
HC 600
Code English
R 600
Code English
BUTANE [II]
Common Name English
HC 600 (HYDROCARBON)
Common Name English
R 600 (ALKANE)
Common Name English
BUTANE [MART.]
Common Name English
N-BUTANE
Common Name English
BUTANE [FCC]
Common Name English
INS NO.943
Code English
Butane [WHO-DD]
Common Name English
INS-943
Code English
Classification Tree Code System Code
JECFA EVALUATION INS-493
Created by admin on Mon Mar 31 18:07:55 GMT 2025 , Edited by admin on Mon Mar 31 18:07:55 GMT 2025
CFR 21 CFR 184.1165
Created by admin on Mon Mar 31 18:07:55 GMT 2025 , Edited by admin on Mon Mar 31 18:07:55 GMT 2025
Code System Code Type Description
EVMPD
SUB21159
Created by admin on Mon Mar 31 18:07:55 GMT 2025 , Edited by admin on Mon Mar 31 18:07:55 GMT 2025
PRIMARY
NCI_THESAURUS
C65276
Created by admin on Mon Mar 31 18:07:55 GMT 2025 , Edited by admin on Mon Mar 31 18:07:55 GMT 2025
PRIMARY
MESH
C046888
Created by admin on Mon Mar 31 18:07:55 GMT 2025 , Edited by admin on Mon Mar 31 18:07:55 GMT 2025
PRIMARY
FDA UNII
6LV4FOR43R
Created by admin on Mon Mar 31 18:07:55 GMT 2025 , Edited by admin on Mon Mar 31 18:07:55 GMT 2025
PRIMARY
PUBCHEM
7843
Created by admin on Mon Mar 31 18:07:55 GMT 2025 , Edited by admin on Mon Mar 31 18:07:55 GMT 2025
PRIMARY
DAILYMED
6LV4FOR43R
Created by admin on Mon Mar 31 18:07:55 GMT 2025 , Edited by admin on Mon Mar 31 18:07:55 GMT 2025
PRIMARY
WIKIPEDIA
BUTANE
Created by admin on Mon Mar 31 18:07:55 GMT 2025 , Edited by admin on Mon Mar 31 18:07:55 GMT 2025
PRIMARY
ECHA (EC/EINECS)
203-448-7
Created by admin on Mon Mar 31 18:07:55 GMT 2025 , Edited by admin on Mon Mar 31 18:07:55 GMT 2025
PRIMARY
RXCUI
1310550
Created by admin on Mon Mar 31 18:07:55 GMT 2025 , Edited by admin on Mon Mar 31 18:07:55 GMT 2025
PRIMARY RxNorm
EPA CompTox
DTXSID7024665
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PRIMARY
SMS_ID
100000089676
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PRIMARY
CHEBI
37808
Created by admin on Mon Mar 31 18:07:55 GMT 2025 , Edited by admin on Mon Mar 31 18:07:55 GMT 2025
PRIMARY
NCI_THESAURUS
C45678
Created by admin on Mon Mar 31 18:07:55 GMT 2025 , Edited by admin on Mon Mar 31 18:07:55 GMT 2025
CONCEPT Industrial Aid
MERCK INDEX
m2787
Created by admin on Mon Mar 31 18:07:55 GMT 2025 , Edited by admin on Mon Mar 31 18:07:55 GMT 2025
PRIMARY Merck Index
HSDB
944
Created by admin on Mon Mar 31 18:07:55 GMT 2025 , Edited by admin on Mon Mar 31 18:07:55 GMT 2025
PRIMARY
CAS
106-97-8
Created by admin on Mon Mar 31 18:07:55 GMT 2025 , Edited by admin on Mon Mar 31 18:07:55 GMT 2025
PRIMARY
ChEMBL
CHEMBL134702
Created by admin on Mon Mar 31 18:07:55 GMT 2025 , Edited by admin on Mon Mar 31 18:07:55 GMT 2025
PRIMARY
Related Record Type Details
ACTIVE MOIETY