MF-498

Details

Stereochemistry	ACHIRAL
Molecular Formula	C32H33N3O7S
Molecular Weight	603.685
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOC1=C2CN(C(=O)C2=C(OCC)C3=CC=CN=C13)C4=CC=C(CS(=O)(=O)NC(=O)CC5=CC=CC=C5OC)C=C4C

InChI

InChIKey=WVLIUERFVJYBNY-UHFFFAOYSA-N

InChI=1S/C32H33N3O7S/c1-5-41-30-23-11-9-15-33-29(23)31(42-6-2)24-18-35(32(37)28(24)30)25-14-13-21(16-20(25)3)19-43(38,39)34-27(36)17-22-10-7-8-12-26(22)40-4/h7-16H,5-6,17-19H2,1-4H3,(H,34,36)

HIDE SMILES / InChI

Molecular Formula	C32H33N3O7S
Molecular Weight	603.685
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Prostanoid EP4 receptor 12 Target ID: CHEMBL1836 Sources: https://www.ncbi.nlm.nih.gov/pubmed/18287210	Antagonist 2849		9.1 null [pKi]

PubMed

Title	Date	PubMed
MF498 [N-{[4-(5,9-Diethoxy-6-oxo-6,8-dihydro-7H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylbenzyl]sulfonyl}-2-(2-methoxyphenyl)acetamide], a selective E prostanoid receptor 4 antagonist, relieves joint inflammation and pain in rodent models of rheumatoid and osteoarthritis.	2008-05	18287210

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:20:17 GMT 2025` Edited by `admin` on `Mon Mar 31 18:20:17 GMT 2025`
Record UNII	6K32LCR80R
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MF-498

Common Name

English

BENZENEACETAMIDE, N-(((4-(5,9-DIETHOXY-6,8-DIHYDRO-6-OXO-7H-PYRROLO(3,4-G)QUINOLIN-7-YL)-3-METHYLPHENYL)METHYL)SULFONYL)-2-METHOXY-

Preferred Name

English

Code System Code Type Description

EPA CompTox

DTXSID701347905

Created by admin on Mon Mar 31 18:20:17 GMT 2025 , Edited by admin on Mon Mar 31 18:20:17 GMT 2025

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PUBCHEM

15948325

Created by admin on Mon Mar 31 18:20:17 GMT 2025 , Edited by admin on Mon Mar 31 18:20:17 GMT 2025

PRIMARY

CAS

915191-42-3

Created by admin on Mon Mar 31 18:20:17 GMT 2025 , Edited by admin on Mon Mar 31 18:20:17 GMT 2025

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FDA UNII

6K32LCR80R

Created by admin on Mon Mar 31 18:20:17 GMT 2025 , Edited by admin on Mon Mar 31 18:20:17 GMT 2025

PRIMARY

Related Record Type Details


					6K32LCR80R

MF-498

ACTIVE MOIETY