DIMESTROL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H24O2
Molecular Weight	296.4034
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC\C(C1=CC=C(OC)C=C1)=C(\CC)C2=CC=C(OC)C=C2

InChI

InChIKey=VQOAQMIKPYNCMV-FMQUCBEESA-N

InChI=1S/C20H24O2/c1-5-19(15-7-11-17(21-3)12-8-15)20(6-2)16-9-13-18(22-4)14-10-16/h7-14H,5-6H2,1-4H3/b20-19+

HIDE SMILES / InChI

Molecular Formula	C20H24O2
Molecular Weight	296.4034
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: https://www.cancer.gov/about-cancer/causes-prevention/risk/hormones/des-fact-sheet | https://www.ncbi.nlm.nih.gov/pubmed/15168959

Dimestrol (Diethylstilbestrol, DES) is a synthetic nonsteroidal estrogen. It was prescribed to pregnant women between 1940 and 1971 to prevent miscarriage, premature labor, and related complications of pregnancy. The use of DES declined after studies in the 1950s showed that it was not effective in preventing these problems. In 1971, the FDA issued a warning that risk of clear cell adenocarcinoma of the vagina and cervix was elevated in young women whose mothers used DES during pregnancy.

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:13:27 UTC 2023` Edited by `admin` on `Fri Dec 15 15:13:27 UTC 2023`
Record UNII	6H0MA01FTS
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DIMESTROL

Common Name

English

STILBESTROL DIMETHYL ETHER

Common Name

English

Dimestrol [WHO-DD]

Common Name

English

DIMETHOXY-DIETHYLSTILBESTROL

Systematic Name

English

DIMESTROL [MI]

Common Name

English

1,1'-((1E)-1,2-DIETHYL-1,2-ETHENEDIYL)BIS(4-METHOXYBENZENE)

Systematic Name

English

(E)-.ALPHA.,.ALPHA.'-DIETHYL-4,4'-DIMETHOXYSTILBENE

Common Name

English

(E)-3,4-BIS(P-METHOXYPHENYL)-3-HEXENE

Common Name

English

Code System Code Type Description

MERCK INDEX

m4504