BROLACONAZOLE

Details

Stereochemistry	RACEMIC
Molecular Formula	C17H15BrN2
Molecular Weight	327.218
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

BrC1=CC=C(C=C1)C(CN2C=CN=C2)C3=CC=CC=C3

InChI

InChIKey=MLHFXOOXBZMGSH-UHFFFAOYSA-N

InChI=1S/C17H15BrN2/c18-16-8-6-15(7-9-16)17(12-20-11-10-19-13-20)14-4-2-1-3-5-14/h1-11,13,17H,12H2

HIDE SMILES / InChI

Molecular Formula	C17H15BrN2
Molecular Weight	327.218
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=19880803&CC=EP&NR=0276583A1&KC=A1 | http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=/netahtml/PTO/srchnum.html&r=1&f=G&l=50&s1=%2720100226943%27.PGNR.&OS=DN/20100226943&RS=DN/20100226943

Brolaconazole is imidazole derivative with potent antimicrobial activity against pathogenic fungi, molds, yeasts, and Gram-positive bacteria. Brolaconazole showed an inhibition band of 20-40 mM against Candida albican and it demonstrates higher activity compare bifonazole. Brolaconazole is useful for the treatment of dermal and vaginal infections such as vaginal candidiasis, tinea corporis, tinea pedis, tinea cruris, and other dermal infections.

Originator

Approval Year

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:45:58 GMT 2025` Edited by `admin` on `Mon Mar 31 18:45:58 GMT 2025`
Record UNII	6CHG505391
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

(±)-1-(P-BROMO-.BETA.-PHENYLPHENETHYL)IMIDAZOLE

Preferred Name

English

BROLACONAZOLE

Official Name

English

brolaconazole [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C514