Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C19H32O7 |
| Molecular Weight | 372.4532 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 7 / 7 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C[C@H](CC[C@H]1C(C)=CC(=O)CC1(C)C)O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O
InChI
InChIKey=NYLNHNDMNOPWAZ-ZLEFDVGRSA-N
InChI=1S/C19H32O7/c1-10-7-12(21)8-19(3,4)13(10)6-5-11(2)25-18-17(24)16(23)15(22)14(9-20)26-18/h7,11,13-18,20,22-24H,5-6,8-9H2,1-4H3/t11-,13+,14-,15-,16+,17-,18-/m1/s1
| Molecular Formula | C19H32O7 |
| Molecular Weight | 372.4532 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 7 / 7 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
DescriptionCurator's Comment: description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/24785825
Curator's Comment: description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/24785825
Byzantionoside B was isolated from the aerial parts of Stachys byzantina as the C-9 epimer of blumenol C glucoside. Byzantionoside B showed osteogenic activity by increasing alkaline phosphatase activity and calcium contents to regulate differentiation and mineralization in human osteoblast cells.
Approval Year
Sample Use Guides
Byzantionoside B significantly increased alkaline phosphatase activity in human osteoblast cells when used at a concentration of 100 μM and also increased the calcium contents of the mineralized matrix. At the same concentration. Byzantionoside B upregulated the mRNA expression of osteopontin, bone morphogenetic protein-2, and runt-related transcription factor 2 in human osteoblast cells.
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 11:08:54 UTC 2023
by
admin
on
Sat Dec 16 11:08:54 UTC 2023
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| Record UNII |
6C3V404S0G
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| Record Status |
Validated (UNII)
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| Record Version |
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-
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14135395
Created by
admin on Sat Dec 16 11:08:54 UTC 2023 , Edited by admin on Sat Dec 16 11:08:54 UTC 2023
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135820-80-3
Created by
admin on Sat Dec 16 11:08:54 UTC 2023 , Edited by admin on Sat Dec 16 11:08:54 UTC 2023
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6C3V404S0G
Created by
admin on Sat Dec 16 11:08:54 UTC 2023 , Edited by admin on Sat Dec 16 11:08:54 UTC 2023
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| Related Record | Type | Details | ||
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PARENT -> CONSTITUENT ALWAYS PRESENT |
Compound was extracted from the dried leaves of N. tabacum (3.5 kg) with 90% EtOH at room temperature and partitioned between EtOAc and H2O.
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