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Details

Stereochemistry ABSOLUTE
Molecular Formula C14H22N6O4.Cu
Molecular Weight 401.908
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PREZATIDE COPPER

SMILES

[Cu++].NCCCC[C@H](NC(=O)[C@H](CC1=C[N-]C=N1)NC(=O)CN)C([O-])=O

InChI

InChIKey=QMIFIFIYYPUVNU-ACMTZBLWSA-L
InChI=1S/C14H24N6O4.Cu/c15-4-2-1-3-10(14(23)24)20-13(22)11(19-12(21)6-16)5-9-7-17-8-18-9;/h7-8,10-11H,1-6,15-16H2,(H4,17,18,19,20,21,22,23,24);/q;+2/p-2/t10-,11-;/m0./s1

HIDE SMILES / InChI

Molecular Formula Cu
Molecular Weight 63.546
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C14H24N6O4
Molecular Weight 340.3782
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Prezatide is a tripeptide molecule consisiting of lysine, glycine and histidine, also known as GHK (glycyl-L-histidyl-L-lysine), that forms a complex with copper ions. Prezatide is used in cosmetic products (skin and hair) and is known help wound healing. Prezatide increases the synthesis and deposition of type I collagen and glycosaminoglycan. It is thought to play a role in the modulation of tissue remodeling by increases the expression of matrix metalloproteinase-2, as well as tissue inhibitor of matrix metalloproteinases-1 and -2. Prezatide has antioxidant activity due to its ability to supply copper for superoxide dismutase and anti-inflammatory ability due to the blockage the of iron (Fe2+) release during injury.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Inactive ingredient
Volu-Firm

Approved Use

Unknown
Substance Class Chemical
Created
by admin
on Mon Mar 31 20:20:36 GMT 2025
Edited
by admin
on Mon Mar 31 20:20:36 GMT 2025
Record UNII
6BJQ43T1I9
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PREZATIDE COPPER
Common Name English
COPPER TRIPEPTIDE-1
INCI  
INCI  
Preferred Name English
GHK COMPLEX WITH COPPER
MI  
Common Name English
L-LYSINE, N2-(N-GLYCYL-L-HISTIDYL)-, COPPER COMPLEX
Common Name English
GHK COMPLEX WITH COPPER [MI]
Common Name English
CG-COPPER PEPTIDE
Brand Name English
COPPER, (N2-(N-GLYCYL-L-HISTIDYL)-L-LYSINATO(2-))-
Common Name English
GHK COPPER
Common Name English
ORISTAR CU-GHK
Brand Name English
COPPER, (GLYCYL-.KAPPA.N-L-HISTIDYL-.KAPPA.N,.KAPPA.N3-L-LYSINATO(2-))-
Common Name English
COPPER PEPTIDE REPAIR COMPLEX
Common Name English
Code System Code Type Description
DRUG BANK
DB14683
Created by admin on Mon Mar 31 20:20:36 GMT 2025 , Edited by admin on Mon Mar 31 20:20:36 GMT 2025
PRIMARY
EPA CompTox
DTXSID20237492
Created by admin on Mon Mar 31 20:20:36 GMT 2025 , Edited by admin on Mon Mar 31 20:20:36 GMT 2025
PRIMARY
FDA UNII
6BJQ43T1I9
Created by admin on Mon Mar 31 20:20:36 GMT 2025 , Edited by admin on Mon Mar 31 20:20:36 GMT 2025
PRIMARY
PUBCHEM
10111685
Created by admin on Mon Mar 31 20:20:36 GMT 2025 , Edited by admin on Mon Mar 31 20:20:36 GMT 2025
PRIMARY
CAS
89030-95-5
Created by admin on Mon Mar 31 20:20:36 GMT 2025 , Edited by admin on Mon Mar 31 20:20:36 GMT 2025
PRIMARY
RXCUI
1314233
Created by admin on Mon Mar 31 20:20:36 GMT 2025 , Edited by admin on Mon Mar 31 20:20:36 GMT 2025
PRIMARY RxNorm
MERCK INDEX
m5722
Created by admin on Mon Mar 31 20:20:36 GMT 2025 , Edited by admin on Mon Mar 31 20:20:36 GMT 2025
PRIMARY Merck Index
DAILYMED
6BJQ43T1I9
Created by admin on Mon Mar 31 20:20:36 GMT 2025 , Edited by admin on Mon Mar 31 20:20:36 GMT 2025
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
PARENT -> SALT/SOLVATE
Related Record Type Details
ACTIVE MOIETY