SLV-310

Details

Stereochemistry	ACHIRAL
Molecular Formula	C25H24FN3O2
Molecular Weight	417.4754
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

FC1=CC2=C(NC=C2C3=CCN(CCCCN4C(=O)C5=C(C=CC=C5)C4=O)CC3)C=C1

InChI

InChIKey=NECJNLXOJRDELU-UHFFFAOYSA-N

InChI=1S/C25H24FN3O2/c26-18-7-8-23-21(15-18)22(16-27-23)17-9-13-28(14-10-17)11-3-4-12-29-24(30)19-5-1-2-6-20(19)25(29)31/h1-2,5-9,15-16,27H,3-4,10-14H2

HIDE SMILES / InChI

Molecular Formula	C25H24FN3O2
Molecular Weight	417.4754
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Tue Apr 01 17:24:12 GMT 2025` Edited by `admin` on `Tue Apr 01 17:24:12 GMT 2025`
Record UNII	69GK99VB9C
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1H-ISOINDOLE-1,3(2H)-DIONE, 2-(4-(4-(5-FLUORO-1H-INDOL-3-YL)-3,6-DIHYDRO-1(2H)-PYRIDINYL)BUTYL)-

Preferred Name

English

SLV-310

Common Name

English

2-(4-(4-(5-FLUORO-1H-INDOL-3-YL)-3,6-DIHYDROPYRIDIN-1(2H)-YL)BUTYL)-1H-ISOINDOLE-1,3(2H)-DIONE

Systematic Name

English

2-(4-(4-(5-FLUORO-1H-INDOL-3-YL)-3,6-DIHYDRO-2H-PYRIDIN-1-YL)BUTYL)ISOINDOLINE-1,3-DIONE

Systematic Name

English

Code System Code Type Description

CAS

264869-71-8

Created by admin on Tue Apr 01 17:24:12 GMT 2025 , Edited by admin on Tue Apr 01 17:24:12 GMT 2025

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PUBCHEM

9888211

Created by admin on Tue Apr 01 17:24:12 GMT 2025 , Edited by admin on Tue Apr 01 17:24:12 GMT 2025

PRIMARY

FDA UNII

69GK99VB9C

Created by admin on Tue Apr 01 17:24:12 GMT 2025 , Edited by admin on Tue Apr 01 17:24:12 GMT 2025

PRIMARY

SMS_ID

300000041438

Created by admin on Tue Apr 01 17:24:12 GMT 2025 , Edited by admin on Tue Apr 01 17:24:12 GMT 2025

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Related Record Type Details


					6TUV1UJA7J

SLV-310 HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Related Record Type Details


					69GK99VB9C

SLV-310

ACTIVE MOIETY

Comments:

SLV 310 is a novel compound combining potent dopamine D 2 receptor antagonism with serotonin reuptake inhibition.


					69GK99VB9C

SLV-310

ACTIVE MOIETY

Comments:

The antipsychotic potency of 6b was demonstrated by the fact that 6b significantly disrupted avoidance behaviour14 in a conditioned avoidance response paradigm in three independent groups of trained rats (ED50=17.5 mg/kg, po, based on the HCl salt of 6b). It can be concluded that 6b is a promising novel antipsychotic indeed, combining strong dopamine D2-receptor antagonism with SRI effects in the same dose range.