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Description

Iodide ion I-125 is radioisotope of iodine with half-life 59.4 days. It decays with the emission of low-energy gamma rays. It is used as a source for bone densitometry devices, protein iodination. Seeds implantations with I-125 are used in the clinics for the treatment of prostate cancer, malignant biliary obstruction, non-small cell lung cancer, colorectal cancer, uveal melanoma, and other tumors.

Approval Year

1976
92
Substance Class Protein
Created
by admin
on Mon Mar 31 20:48:27 GMT 2025
Edited
by admin
on Mon Mar 31 20:48:27 GMT 2025
Protein Type SERUM PROTEIN; RADIOLABELED
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
68WQQ3N9TI
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
HUMAN SERUM ALBUMIN I-125
Common Name English
IODINATED (125I) HUMAN SERUM ALBUMIN
INN  
INN  
Preferred Name English
JEANATOPE
Brand Name English
125 I HSA
Common Name English
ALBUMOTOPE I-125
Brand Name English
ALBUMIN, IODINATED I 125 SERUM
USAN  
USAN  
Official Name English
Iodinated (125 i) human serum albumin [WHO-DD]
Common Name English
ALBUMIN,IODINATED SERUM,I-125
VANDF  
Common Name English
IHSA I-125
Common Name English
IODINATED ((SUP 125)I) HUMAN SERUM ALBUMIN
Common Name English
IODINATED HUMAN SERUM ALBUMIN (I-125)
Common Name English
HSA I-125
Common Name English
iodinated (¹²?I) human serum albumin [INN]
Common Name English
Albumin, blood serum, labeled with iodine-125
Common Name English
125-I-HSA
Common Name English
ALBUMIN,IODINATED I-125 SERUM [VANDF]
Common Name English
ALBUMIN IODINATED I-125 SERUM
ORANGE BOOK  
Common Name English
ALBUMIN IODINATED I-125 SERUM [ORANGE BOOK]
Common Name English
ALBUMIN,IODINATED SERUM,I-125 [VANDF]
Common Name English
IODINATED I-125 SERUM ALBUMIN
Common Name English
125 I-HSA
Common Name English
ALBUMIN, IODINATED I-125 SERUM
Common Name English
IODINATED I 125 SERUM ALBUMIN
Common Name English
ALBUMIN, IODINATED I 125 SERUM [USAN]
Common Name English
ALBUMIN,IODINATED I-125 SERUM
VANDF  
Common Name English
RISA-125
Brand Name English
HUMAN ALBUMIN I-125
Common Name English
Classification Tree Code System Code
NDF-RT N0000000205
Created by admin on Mon Mar 31 20:48:27 GMT 2025 , Edited by admin on Mon Mar 31 20:48:27 GMT 2025
NDF-RT N0000177914
Created by admin on Mon Mar 31 20:48:27 GMT 2025 , Edited by admin on Mon Mar 31 20:48:27 GMT 2025
NCI_THESAURUS C2124
Created by admin on Mon Mar 31 20:48:27 GMT 2025 , Edited by admin on Mon Mar 31 20:48:27 GMT 2025
WHO-ATC V09GB02
Created by admin on Mon Mar 31 20:48:27 GMT 2025 , Edited by admin on Mon Mar 31 20:48:27 GMT 2025
WHO-VATC QV09GB02
Created by admin on Mon Mar 31 20:48:27 GMT 2025 , Edited by admin on Mon Mar 31 20:48:27 GMT 2025
Code System Code Type Description
NCI_THESAURUS
C87395
Created by admin on Mon Mar 31 20:48:27 GMT 2025 , Edited by admin on Mon Mar 31 20:48:27 GMT 2025
PRIMARY
EVMPD
SUB127365
Created by admin on Mon Mar 31 20:48:27 GMT 2025 , Edited by admin on Mon Mar 31 20:48:27 GMT 2025
ALTERNATIVE
SMS_ID
100000092389
Created by admin on Mon Mar 31 20:48:27 GMT 2025 , Edited by admin on Mon Mar 31 20:48:27 GMT 2025
PRIMARY
EVMPD
SUB127166
Created by admin on Mon Mar 31 20:48:27 GMT 2025 , Edited by admin on Mon Mar 31 20:48:27 GMT 2025
ALTERNATIVE
DAILYMED
68WQQ3N9TI
Created by admin on Mon Mar 31 20:48:27 GMT 2025 , Edited by admin on Mon Mar 31 20:48:27 GMT 2025
PRIMARY
RXCUI
317177
Created by admin on Mon Mar 31 20:48:27 GMT 2025 , Edited by admin on Mon Mar 31 20:48:27 GMT 2025
PRIMARY RxNorm
FDA UNII
68WQQ3N9TI
Created by admin on Mon Mar 31 20:48:27 GMT 2025 , Edited by admin on Mon Mar 31 20:48:27 GMT 2025
PRIMARY
LACTMED
Albumin, Iodinated I 125 Serum
Created by admin on Mon Mar 31 20:48:27 GMT 2025 , Edited by admin on Mon Mar 31 20:48:27 GMT 2025
PRIMARY
DRUG BANK
DB09429
Created by admin on Mon Mar 31 20:48:27 GMT 2025 , Edited by admin on Mon Mar 31 20:48:27 GMT 2025
PRIMARY
INN
2805
Created by admin on Mon Mar 31 20:48:27 GMT 2025 , Edited by admin on Mon Mar 31 20:48:27 GMT 2025
PRIMARY
EVMPD
SUB12025MIG
Created by admin on Mon Mar 31 20:48:27 GMT 2025 , Edited by admin on Mon Mar 31 20:48:27 GMT 2025
PRIMARY
ChEMBL
CHEMBL1201452
Created by admin on Mon Mar 31 20:48:27 GMT 2025 , Edited by admin on Mon Mar 31 20:48:27 GMT 2025
PRIMARY
From To
1_53 1_62
1_75 1_91
1_90 1_101
1_124 1_169
1_168 1_177
1_200 1_246
1_245 1_253
1_265 1_279
1_316 1_361
1_360 1_369
1_392 1_438
1_437 1_448
1_461 1_477
1_476 1_487
1_514 1_559
1_558 1_567
Related Record Type Details
HUMAN SERUM ALBUMIN I-125
ACTIVE MOIETY
Structure of IODIDE ION I-125
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
AMINO_ACID_SUBSTITUTION RESIDUE_SPECIFIC Y IOTYROSINE I-125 9ZY3O14KI4
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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