PRAZARELIX

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C80H102ClN23O12
Molecular Weight	1613.2688
Optical Activity	UNSPECIFIED
Defined Stereocenters	10 / 10
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)C[C@H](NC(=O)[C@@H](CC1=CC=C(NC2=NN=C(N)N2)C=C1)NC(=O)[C@H](CC3=CC=C(NC4=NN=C(N)N4)C=C3)NC(=O)[C@H](CO)NC(=O)[C@@H](CC5=CC=CN=C5)NC(=O)[C@@H](CC6=CC=C(Cl)C=C6)NC(=O)[C@@H](CC7=CC=C8C=CC=CC8=C7)NC(C)=O)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N9CCC[C@H]9C(=O)N[C@H](C)C(N)=O

InChI

InChIKey=VLGKQBGBPIVGBX-ZVSGBDDQSA-N

InChI=1S/C80H102ClN23O12/c1-44(2)35-59(68(108)91-58(16-9-10-33-86-45(3)4)76(116)104-34-12-17-66(104)75(115)87-46(5)67(82)107)92-70(110)62(38-49-21-28-56(29-22-49)89-79-98-77(83)100-102-79)94-72(112)63(39-50-23-30-57(31-24-50)90-80-99-78(84)101-103-80)96-74(114)65(43-105)97-73(113)64(41-52-13-11-32-85-42-52)95-71(111)61(37-48-19-26-55(81)27-20-48)93-69(109)60(88-47(6)106)40-51-18-25-53-14-7-8-15-54(53)36-51/h7-8,11,13-15,18-32,36,42,44-46,58-66,86,105H,9-10,12,16-17,33-35,37-41,43H2,1-6H3,(H2,82,107)(H,87,115)(H,88,106)(H,91,108)(H,92,110)(H,93,109)(H,94,112)(H,95,111)(H,96,114)(H,97,113)(H4,83,89,98,100,102)(H4,84,90,99,101,103)/t46-,58+,59+,60-,61-,62-,63+,64-,65+,66+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C80H102ClN23O12
Molecular Weight	1613.2688
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	10 / 10
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: Aronson, J.K. (2014) Meyler's Side Effects of Drugs 15E, retrieved from: https://books.google.ru/books?id=tqsXzG1W8HgC | Maamir, S., Haghi, A.K. (2015) Mechanical and Physico-Chemical Characteristics of Modified Materials, page 299, retrieved from: https://books.google.ru/books?id=EN-YCgAAQBAJ

Prazarelix is gonadorelin (GnRH) antagonist. It is primarily used in assisted reproduction to control ovulation. The drug works by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of luteinizing hormone (LH) and follicle-stimulating hormone (FSH).

Approval Year

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:41:29 GMT 2025` Edited by `admin` on `Mon Mar 31 18:41:29 GMT 2025`
Record UNII	68HX54O1VL
Record Status	`FAILED`
Record Version

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Name

Type

Language

PRAZARELIX

Official Name

English

N-ACETYL-3-(2-NAPHTHYL)-D-ALANYL-P-CHLORO-D-PHENYLALANYL-3-(3-PYRIDYL)-D-ALANYL-L-SERYL-P-((5-AMINO-S-TRIAZOL-3-YL)AMINO)-L-PHENYLALANYL-P-((5-AMINO-S-TRIAZOL-3-YL)AMINO)-D-PHENYLALANYL-L-LEUCYL-N6-ISOPROPYL-L-LYSYL-L-PROLYL-D-ALANINAMIDE

Preferred Name

English

prazarelix [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C2092