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Description
Curator's Comment: description was created based on several sources, including http://www.mfc.co.jp/english/eng/product/sanferol/index.html

Ferric Ammonium EDTA Solution is normally used as a photographic chemical for a bleaching agent in the process of colour washing. It is also used as a complexing, and oxidizing agent & as a fertilizer and catalyst. EDTA acid are colourless, water-soluble solid that are widely used to dissolve scale. The usefulness of these ammonium salts arise because of its role as a chelating agent, i.e. its ability to "sequester" metal ions such as Ca2+ and Fe3+.

Originator

Monsanto Chemicals
40
Curator's Comment: The relation between phosphate level and ferric citrate consumption was first discovered in 1940s.

Approval Year

1921
1468
Targets

Targets

Primary TargetPharmacologyConditionPotency
Activator
1447
Chelating Agent
139
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Basic research
Unknown

Approved Use

Unknown
Primary
Approved
8583
SANFEROL

Approved Use

It has also been reported that SFC preparation improved iron deficiency in a pregnant woman with iron deficiency anemia whose hemoglobin level had not increased after administration of other iron preparations such as ferrous fumarate. A dairy supplemental dose of SFC improved iron deficiency in young women with iron deficiency.
Inactive ingredient
Approved
8583
Oxycontin

Approved Use

OxyContin is used in the treatment of chronic pain; pain and belongs to the drug class narcotic analgesics.

Launch Date

1998
Palliative
Approved
8583
AURYXIA

Approved Use

Ferric Citrate is a phosphate binder indicated for the control of serum phosphorus levels in patients with chronic kidney disease on dialysis.

Launch Date

2014
PubMed

PubMed

TitleDatePubMed
Phosphorus recovery from biogas slurry by ultrasound/H2O2 digestion coupled with HFO/biochar adsorption process.
2017-02
Superior electrochemical performance of N-doped nanocrystalline FeF3/C with a single-step solid-state process.
2016-10-04
Heme Binding by Corynebacterium diphtheriae HmuT: Function and Heme Environment.
2015-11-03
Microwave assisted convenient one-pot synthesis of coumarin derivatives via Pechmann condensation catalyzed by FeF3 under solvent-free conditions and antimicrobial activities of the products.
2014-08-26
FeF(3) catalyzed cascade C-C and C-N bond formation: synthesis of differentially substituted triheterocyclic benzothiazole functionalities under solvent-free condition.
2014-05
Finnish wallpaper pigments in the 18th-19th century: presence of KFe3(CrO4)2(OH)6 and odd pigment mixtures.
2013-04
Thermal behavior study and decomposition kinetics of amiodarone hydrochloride under isothermal conditions.
2011-06
Fabrication of FeF3 Nanoflowers on CNT branches and their application to high power lithium rechargeable batteries.
2010-12-07
Interaction of omapatrilat with FD&C Blue No. 2 lake during dissolution of modified release tablets.
2007-07-18
Non-invasive and non-destructive micro-XRF and micro-Raman analysis of a decorative wallpaper from the beginning of the 19th century.
2007-02
New phosphate binding agents: ferric compounds.
1999-06
Effect of physical exercise and vitamin C on absorption of ferric sodium citrate.
1996-12
Carcinogenicity studies on natural and man-made fibres with the intraperitoneal test in rats.
1989
Contact dermatitis to yellow iron oxide.
1985-08
Biological availability of iron supplements for rats, chicks and humans.
1976-02
The absorption of iron as supplements in infant cereal and infant formulas.
1975-05
The formation of ferritin from apoferritin. Catalytic action of apoferritin.
1973-10
The formation of ferritin from apoferritin. Kinetics and mechanism of iron uptake.
1972-01
[Effects of ferric fluoride compounds on dental enamel].
1954-11-15
Patents

Patents

20090216060
40
6258758
40
US 5206265 A
40
US2385188
40
US4364871
40
US6881255
40
US6903235
40
US7198668
40

Sample Use Guides

In Vivo Use Guide
Curator's Comment: Iron oxides black, red and yellow are intended to be used as colourants in feedingstuffs for all animal species without dose or age restriction. The applicant recommends 500–1,200 mg/kg of the additives in complete (and complementary) feedingstuffs as standard dose. http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2016.4482/full
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Bovine enamel was treated with 10 mM FeF3 (Ferric fluoride)
Substance Class Polymer
Created
by admin
on Tue Apr 01 20:39:22 GMT 2025
Edited
by admin
on Tue Apr 01 20:39:22 GMT 2025
Record UNII
6897GXD6OE
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FERRIC CARBOXYMALTOSE
INN   MART.   ORANGE BOOK   USAN   VANDF   WHO-DD  
USAN   INN  
Official Name English
INJECTAFER
Preferred Name English
POLYNUCLEAR IRON (III)-HYDROXIDE 4(R)-(POLY-(1->4)-O-.ALPHA.-D-GLUCOPYRANOSYL)-OXY-2(R),3(S),5(R), 6-TETRAHYDROXY-HEXANOATE
Common Name English
IRON(3+) HYDROXIDE OXIDE POLY-(1->4)-.ALPHA.-D-GLUCOPYRANOSYL-(1->4)-D-GLUCONATE HYDRATE
Common Name English
Ferric Carboxymaltose [WHO-DD]
Common Name English
FERRIC CARBOXYMALTOSE [ORANGE BOOK]
Common Name English
FERRIC CARBOXYMALTOSE [MART.]
Common Name English
ferric carboxymaltose [INN]
Common Name English
VIT-45
Code English
FERRIC CARBOXYMALTOSE [VANDF]
Common Name English
FERRIC CARBOXYMALTOSE [JAN]
Common Name English
FERRIC CARBOXYMALTOSE [USAN]
Common Name English
IRON DEXTRI-MALTOSE
Common Name English
Code System Code Type Description
FDA UNII
6897GXD6OE
Created by admin on Tue Apr 01 20:39:22 GMT 2025 , Edited by admin on Tue Apr 01 20:39:22 GMT 2025
PRIMARY
ChEMBL
CHEMBL2108597
Created by admin on Tue Apr 01 20:39:22 GMT 2025 , Edited by admin on Tue Apr 01 20:39:22 GMT 2025
PRIMARY
CAS
1461680-64-7
Created by admin on Tue Apr 01 20:39:22 GMT 2025 , Edited by admin on Tue Apr 01 20:39:22 GMT 2025
PRIMARY
DRUG CENTRAL
5128
Created by admin on Tue Apr 01 20:39:22 GMT 2025 , Edited by admin on Tue Apr 01 20:39:22 GMT 2025
PRIMARY
USAN
SS-40
Created by admin on Tue Apr 01 20:39:22 GMT 2025 , Edited by admin on Tue Apr 01 20:39:22 GMT 2025
PRIMARY
RXCUI
1433693
Created by admin on Tue Apr 01 20:39:22 GMT 2025 , Edited by admin on Tue Apr 01 20:39:22 GMT 2025
PRIMARY RxNorm
SMS_ID
100000134826
Created by admin on Tue Apr 01 20:39:22 GMT 2025 , Edited by admin on Tue Apr 01 20:39:22 GMT 2025
PRIMARY
INN
8853
Created by admin on Tue Apr 01 20:39:22 GMT 2025 , Edited by admin on Tue Apr 01 20:39:22 GMT 2025
PRIMARY
CAS
9007-72-1
Created by admin on Tue Apr 01 20:39:22 GMT 2025 , Edited by admin on Tue Apr 01 20:39:22 GMT 2025
ALTERNATIVE
NCI_THESAURUS
C166915
Created by admin on Tue Apr 01 20:39:22 GMT 2025 , Edited by admin on Tue Apr 01 20:39:22 GMT 2025
PRIMARY
EVMPD
SUB66620
Created by admin on Tue Apr 01 20:39:22 GMT 2025 , Edited by admin on Tue Apr 01 20:39:22 GMT 2025
PRIMARY
DAILYMED
6897GXD6OE
Created by admin on Tue Apr 01 20:39:22 GMT 2025 , Edited by admin on Tue Apr 01 20:39:22 GMT 2025
PRIMARY
MESH
C522335
Created by admin on Tue Apr 01 20:39:22 GMT 2025 , Edited by admin on Tue Apr 01 20:39:22 GMT 2025
PRIMARY
PUBCHEM
86278165
Created by admin on Tue Apr 01 20:39:22 GMT 2025 , Edited by admin on Tue Apr 01 20:39:22 GMT 2025
PRIMARY
LACTMED
Ferric Carboxymaltose
Created by admin on Tue Apr 01 20:39:22 GMT 2025 , Edited by admin on Tue Apr 01 20:39:22 GMT 2025
PRIMARY
DRUG BANK
DB08917
Created by admin on Tue Apr 01 20:39:22 GMT 2025 , Edited by admin on Tue Apr 01 20:39:22 GMT 2025
PRIMARY
Display Structure of FERRIC CARBOXYMALTOSE
Related Record Type Details
Structure of FERRIC CATION
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:COMPLEX AVERAGE CHEMICAL
NIH
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