Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C14H19NO2.ClH |
| Molecular Weight | 269.767 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CC(=O)O[C@@H]([C@H]1CCCCN1)C2=CC=CC=C2
InChI
InChIKey=LDPSCUMJCVDWCB-DTPOWOMPSA-N
InChI=1S/C14H19NO2.ClH/c1-11(16)17-14(12-7-3-2-4-8-12)13-9-5-6-10-15-13;/h2-4,7-8,13-15H,5-6,9-10H2,1H3;1H/t13-,14-;/m1./s1
| Molecular Formula | C14H19NO2 |
| Molecular Weight | 233.3062 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Levophacetoperane is a piperidine derivative. Levofacetoperane is a sympathomimetic central nervous system stimulant and is commonly used to treat depression. Levophacetoperane is also a known analeptic and is strongly linked to apnea reversal in dogs after a single intravenous injection.
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: GO:0051620 Sources: https://www.ncbi.nlm.nih.gov/pubmed/29714 |
|||
Target ID: GO:0090494 Sources: https://www.ncbi.nlm.nih.gov/pubmed/29714 |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Isolation and detection of methylphenidate, phacetoperane and some other sympatomimetic central nervous stimulants with special reference to doping. I. Gas chromatographic detection procedure with electron capture detection for some secondary amines. | 1975-03-26 |
|
| [FOREIGN PSYCHOPHARMACOLOGICAL DRUGS: LEVOFACETOPERANE (8228 RP)]. | 1964-10-31 |
|
| [Obesity in pregnancy. Trial of RP 8228. 1-Phenyl-1-(2-piperidyl)-1-acetoxymethane HCi. Threolevogyric form]. | 1963-01 |
|
| [The present status of RP-8228 in psychiatric therapeutics. Apropos of 32 recent cases]. | 1962-10-28 |
|
| [Clinical study of a new psychoactive drug in psychiatry, RP-8228 or threo-levo-1-phenyl-1-(2-piperidyl)-1-acetoxymethane HCl]. | 1962-04 |
|
| The stimulating effect of RP 8228 on inactive psychiatric patients. | 1961-11-01 |
|
| [Clinical tests of the activity of RP 8228 (phacetoperane) in an oligophrenic child]. | 1960 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 17:55:56 GMT 2025
by
admin
on
Mon Mar 31 17:55:56 GMT 2025
|
| Record UNII |
67UU667C62
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Preferred Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
76957863
Created by
admin on Mon Mar 31 17:55:56 GMT 2025 , Edited by admin on Mon Mar 31 17:55:56 GMT 2025
|
PRIMARY | |||
|
23257-56-9
Created by
admin on Mon Mar 31 17:55:56 GMT 2025 , Edited by admin on Mon Mar 31 17:55:56 GMT 2025
|
PRIMARY | |||
|
m6791
Created by
admin on Mon Mar 31 17:55:56 GMT 2025 , Edited by admin on Mon Mar 31 17:55:56 GMT 2025
|
PRIMARY | Merck Index | ||
|
DTXSID20945949
Created by
admin on Mon Mar 31 17:55:56 GMT 2025 , Edited by admin on Mon Mar 31 17:55:56 GMT 2025
|
PRIMARY | |||
|
245-536-8
Created by
admin on Mon Mar 31 17:55:56 GMT 2025 , Edited by admin on Mon Mar 31 17:55:56 GMT 2025
|
PRIMARY | |||
|
67UU667C62
Created by
admin on Mon Mar 31 17:55:56 GMT 2025 , Edited by admin on Mon Mar 31 17:55:56 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
PARENT -> SALT/SOLVATE |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
ACTIVE MOIETY |