Approval Year
Substance Class |
Structurally Diverse
Created
by
admin
on
Edited
Sat Dec 16 19:12:21 GMT 2023
by
admin
on
Sat Dec 16 19:12:21 GMT 2023
|
Source Materials Class | ORGANISM |
Source Materials Type | AUTOLOGOUS HUMAN |
Source Materials State | LIVE GENETICALLY MODIFIED |
Source Materials Parent | |
Part | BLOOD |
Fraction Material Type | CELL |
Fraction Name | T lymphocytes |
Record UNII |
67B9LP62ET
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Record Status |
Validated (UNII)
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Record Version |
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-
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Official Name | English | ||
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Common Name | English | ||
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Common Name | English |
Code System | Code | Type | Description | ||
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12215
Created by
admin on Sat Dec 16 19:12:21 GMT 2023 , Edited by admin on Sat Dec 16 19:12:21 GMT 2023
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PRIMARY | |||
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67B9LP62ET
Created by
admin on Sat Dec 16 19:12:21 GMT 2023 , Edited by admin on Sat Dec 16 19:12:21 GMT 2023
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PRIMARY |
Related Record | Type | Details | ||
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TARGET->CYTOTOXIC T-CELL |
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Related Record | Type | Details | ||
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ACTIVE MOIETY |
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Agent Modifications
Modification Process | Modification Role | Modification Type | Amount | Fragment Name | Fragment ID |
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LENTIVIRAL TRANSFECTION | TRANSFECTION | BIOLOGICAL | Satricabtagene autoleucel lentiviral vector | 8TQ83W598K | |
CULTURE | ACTIVATOR | BIOLOGICAL | UNSPECIFIED SUBSTANCE | 4e4ac683 | |
CULTURE | EXPANSION | BIOLOGICAL | HUMAN INTERLEUKIN-2 | FNO32LO217 |
Structural Modifications
Modification Type | Location Site | Location Type | Residue Modified | Extent | Fragment Name | Fragment Approval |
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VECTOR EXPRESSED PROTEIN | Satricabtagene autoleucel CAR-T receptor | M4K5SHK9L2 | ||||
INSERTED GENE EXPRESSION VECTOR | Satricabtagene autoleucel transgene insert | SU4E6EK3MX |
Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
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ENHANCED ACTIVATION | BIOLOGICAL |
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