Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C13H9N2O3S.Na |
| Molecular Weight | 296.277 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].[O-]S(=O)(=O)C1=CC=C2NC(=NC2=C1)C3=CC=CC=C3
InChI
InChIKey=JNUBZSFXMKCDFD-UHFFFAOYSA-M
InChI=1S/C13H10N2O3S.Na/c16-19(17,18)10-6-7-11-12(8-10)15-13(14-11)9-4-2-1-3-5-9;/h1-8H,(H,14,15)(H,16,17,18);/q;+1/p-1
| Molecular Formula | C13H9N2O3S |
| Molecular Weight | 273.287 |
| Charge | -1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | Na |
| Molecular Weight | 22.9898 |
| Charge | 1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
DescriptionSources: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=611798eb-4004-40e8-b7ff-345136253975Curator's Comment: description was created based on several sources, including:
http://www.ncbi.nlm.nih.gov/pubmed/23112351
Sources: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=611798eb-4004-40e8-b7ff-345136253975
Curator's Comment: description was created based on several sources, including:
http://www.ncbi.nlm.nih.gov/pubmed/23112351
Ensulizole (INN) (phenylbenzimidazole sulfonic acid) is a common sunscreen agent. In 1999, the United States Food and Drug Administration regulated that the name ensulizole be used on sunscreen labels in the United States. It is a selective UVB filter, allowing almost all UVA transmission. The scope of UVB is 290 to 340 nanometers whereas the UVA range is 320 to 400 nanometers. For better UVA protection, it must be paired with avobenzone, titanium dioxide, or zinc oxide; outside of the United States it can also be paired with a UV absorber of the Tinosorb or Mexoryl types. Because is water-soluble, it has the characteristic of feeling lighter on skin. As such, it is often used in sunscreen lotions or moisturizers whose aesthetic goal is a non-greasy finish. The free acid is poorly soluble in water, so it is only used as its soluble salts
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Comparison of the hanson microette and the Van Kel apparatus for in vitro release testing of topical semisolid formulations. | 2001 Oct |
|
| Photophysical and photochemical studies of 2-phenylbenzimidazole and UVB sunscreen 2-phenylbenzimidazole-5-sulfonic acid. | 2002 Feb |
|
| Sensitive sequential-injection system for the determination of 2-phenylbenzimidazole-5-sulphonic acid in human urine samples using on-line solid-phase extraction coupled with fluorimetric detection. | 2003 Mar 1 |
|
| Novel nanotubes from a cationic surfactant and an anionic stiff aromatic counter-ion. | 2006 Sep 14 |
|
| Indirect fluorescent determination of selected nitro-aromatic and pharmaceutical compounds via UV-photolysis of 2-phenylbenzimidazole-5-sulfonate. | 2008 Feb 15 |
|
| Multiclass determination of sunscreen chemicals in water samples by liquid chromatography-tandem mass spectrometry. | 2008 Feb 15 |
|
| Phase behavior of aqueous mixtures of 2-phenylbenzimidazole-5-sulfonic acid and cetyltrimethylammonium bromide: hydrogels, vesicles, tubules, and ribbons. | 2008 Mar 13 |
|
| The sunscreen agent 2-phenylbenzimidazole-5-sulfonic acid photosensitizes the formation of oxidized guanines in cellulo after UV-A or UV-B exposure. | 2010 Oct |
|
| Quantum chemical investigation and experimental verification on the aquatic photochemistry of the sunscreen 2-phenylbenzimidazole-5-sulfonic acid. | 2010 Oct 1 |
|
| Occurrence of xenobiotics in gray water and removal in three biological treatment systems. | 2010 Sep 1 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 01:43:12 GMT 2023
by
admin
on
Sat Dec 16 01:43:12 GMT 2023
|
| Record UNII |
66LQ48A9BT
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Brand Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Official Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
23663543
Created by
admin on Sat Dec 16 01:43:12 GMT 2023 , Edited by admin on Sat Dec 16 01:43:12 GMT 2023
|
PRIMARY | |||
|
100000078294
Created by
admin on Sat Dec 16 01:43:12 GMT 2023 , Edited by admin on Sat Dec 16 01:43:12 GMT 2023
|
PRIMARY | |||
|
66LQ48A9BT
Created by
admin on Sat Dec 16 01:43:12 GMT 2023 , Edited by admin on Sat Dec 16 01:43:12 GMT 2023
|
PRIMARY | |||
|
DTXSID601021879
Created by
admin on Sat Dec 16 01:43:12 GMT 2023 , Edited by admin on Sat Dec 16 01:43:12 GMT 2023
|
PRIMARY | |||
|
m4917
Created by
admin on Sat Dec 16 01:43:12 GMT 2023 , Edited by admin on Sat Dec 16 01:43:12 GMT 2023
|
PRIMARY | Merck Index | ||
|
SUB12680MIG
Created by
admin on Sat Dec 16 01:43:12 GMT 2023 , Edited by admin on Sat Dec 16 01:43:12 GMT 2023
|
PRIMARY | |||
|
5997-53-5
Created by
admin on Sat Dec 16 01:43:12 GMT 2023 , Edited by admin on Sat Dec 16 01:43:12 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
PARENT -> SALT/SOLVATE |
|
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
ACTIVE MOIETY |
|