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Details

Stereochemistry ACHIRAL
Molecular Formula C20H25NO.C6H3N3O7
Molecular Weight 524.5225
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NORMETHADONE PICRATE

SMILES

OC1=C(C=C(C=C1[N+]([O-])=O)[N+]([O-])=O)[N+]([O-])=O.CCC(=O)C(CCN(C)C)(C2=CC=CC=C2)C3=CC=CC=C3

InChI

InChIKey=JRELAUZHQMUKRI-UHFFFAOYSA-N
InChI=1S/C20H25NO.C6H3N3O7/c1-4-19(22)20(15-16-21(2)3,17-11-7-5-8-12-17)18-13-9-6-10-14-18;10-6-4(8(13)14)1-3(7(11)12)2-5(6)9(15)16/h5-14H,4,15-16H2,1-3H3;1-2,10H

HIDE SMILES / InChI

Molecular Formula C6H3N3O7
Molecular Weight 229.1039
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C20H25NO
Molecular Weight 295.4186
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Normethadone is a derivate of opioid analgetic methadone, used as component of antitussive drops in Canada. Illicit drug.

CNS Activity

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Target ID: P33535|||Q64064
Gene ID: 25601.0
Gene Symbol: Oprm1
Target Organism: Rattus norvegicus (Rat)
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Cophylac

Approved Use

Cough
PubMed

PubMed

TitleDatePubMed
Simultaneous screening and quantification of 25 opioid drugs in post-mortem blood and urine by liquid chromatography-tandem mass spectrometry.
2009 Apr 15

Sample Use Guides

Cophylac (normethadone HCl 10 mg and p-hydroxyephedrine HCl 20 mg): 15 drops twice daily
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Thu Jul 06 16:51:26 UTC 2023
Edited
by admin
on Thu Jul 06 16:51:26 UTC 2023
Record UNII
632S02T2CC
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NORMETHADONE PICRATE
Common Name English
3-HEXANONE, 6-(DIMETHYLAMINO)-4,4-DIPHENYL-, COMPD. WITH 2,4,6-TRINITROPHENOL (1:1)
Systematic Name English
6-DIMETHYLAMINO-4,4-DIPHENYL-3-HEXANONE PICRATE
Systematic Name English
NSC-400426
Code English
3-HEXANONE, 6-(DIMETHYLAMINO)-4,4-DIPHENYL-, PICRATE
Systematic Name English
Code System Code Type Description
EPA CompTox
DTXSID60975280
Created by admin on Thu Jul 06 16:51:26 UTC 2023 , Edited by admin on Thu Jul 06 16:51:26 UTC 2023
PRIMARY
PUBCHEM
343874
Created by admin on Thu Jul 06 16:51:26 UTC 2023 , Edited by admin on Thu Jul 06 16:51:26 UTC 2023
PRIMARY
NSC
400426
Created by admin on Thu Jul 06 16:51:26 UTC 2023 , Edited by admin on Thu Jul 06 16:51:26 UTC 2023
PRIMARY
FDA UNII
632S02T2CC
Created by admin on Thu Jul 06 16:51:26 UTC 2023 , Edited by admin on Thu Jul 06 16:51:26 UTC 2023
PRIMARY
CAS
5988-50-1
Created by admin on Thu Jul 06 16:51:26 UTC 2023 , Edited by admin on Thu Jul 06 16:51:26 UTC 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE