AMPYZINE

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NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H9N3
Molecular Weight	123.1558
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of AMPYZINE

Structure Search

SMILES

CN(C)C1=CN=CC=N1

InChI

InChIKey=UUINNXPPLPDRQX-UHFFFAOYSA-N

InChI=1S/C6H9N3/c1-9(2)6-5-7-3-4-8-6/h3-5H,1-2H3

HIDE SMILES / InChI

Molecular Formula	C6H9N3
Molecular Weight	123.1558
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=19660202&CC=GB&NR=1019219A&KC=A | https://books.google.ru/books?id=r-eqWrMoO18C&pg=PA298&lpg=PA298&redir_esc=y#v=onepage&q&f=false retrieved from The Organic Chemistry of Drug Synthesis By Daniel Lednicer, Lester A. Mitscher, Gunda I. Georg, p.298 | https://books.google.ru/books?id=0vXTBwAAQBAJ&pg=PA436&lpg=PA436&dq=AMPYZINE retrieved from The Dictionary of Drugs: Chemical Data. Chemical Data, Structures and Bibliographies. Editors: Elks, J., p.436

Ampyzine is a pyrazine derivative patented by Warner-Lambert Pharmaceutical Co. as a central nervous system stimulant.

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
2,3-Diaminopyrazines as Rho kinase inhibitors.	2010-02-01	20022494

Patents

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:44:48 GMT 2025` Edited by `admin` on `Mon Mar 31 18:44:48 GMT 2025`
Record UNII	630GTK993N
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

AMPYZINE

Official Name

English

ampyzine [INN]

Preferred Name

English

PYRAZINAMINE, N,N-DIMETHYL-

Systematic Name

English

(DIMETHYLAMINO)PYRAZINE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C47795

Created by admin on Mon Mar 31 18:44:48 GMT 2025 , Edited by admin on Mon Mar 31 18:44:48 GMT 2025

Code System Code Type Description

EPA CompTox

DTXSID80200147

Created by admin on Mon Mar 31 18:44:48 GMT 2025 , Edited by admin on Mon Mar 31 18:44:48 GMT 2025

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FDA UNII

630GTK993N

Created by admin on Mon Mar 31 18:44:48 GMT 2025 , Edited by admin on Mon Mar 31 18:44:48 GMT 2025

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ChEMBL

CHEMBL2110770

Created by admin on Mon Mar 31 18:44:48 GMT 2025 , Edited by admin on Mon Mar 31 18:44:48 GMT 2025

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WIKIPEDIA

AMPYZINE

Created by admin on Mon Mar 31 18:44:48 GMT 2025 , Edited by admin on Mon Mar 31 18:44:48 GMT 2025

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PUBCHEM

23483

Created by admin on Mon Mar 31 18:44:48 GMT 2025 , Edited by admin on Mon Mar 31 18:44:48 GMT 2025

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EVMPD

SUB05491MIG

Created by admin on Mon Mar 31 18:44:48 GMT 2025 , Edited by admin on Mon Mar 31 18:44:48 GMT 2025

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INN

1899

Created by admin on Mon Mar 31 18:44:48 GMT 2025 , Edited by admin on Mon Mar 31 18:44:48 GMT 2025

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NCI_THESAURUS

C79869

Created by admin on Mon Mar 31 18:44:48 GMT 2025 , Edited by admin on Mon Mar 31 18:44:48 GMT 2025

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SMS_ID

100000086916

Created by admin on Mon Mar 31 18:44:48 GMT 2025 , Edited by admin on Mon Mar 31 18:44:48 GMT 2025

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CAS

5214-29-9

Created by admin on Mon Mar 31 18:44:48 GMT 2025 , Edited by admin on Mon Mar 31 18:44:48 GMT 2025

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Related Record Type Details


					B8L03Q9MME

AMPYZINE SULFATE

SALT/SOLVATE -> PARENT

Related Record Type Details


					630GTK993N

AMPYZINE

ACTIVE MOIETY