U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C13H12O7S2
Molecular Weight 344.36
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SULTOSILIC ACID

SMILES

CC1=CC=C(C=C1)S(=O)(=O)OC2=CC(=C(O)C=C2)S(O)(=O)=O

InChI

InChIKey=SVXZTCUBEFUKRQ-UHFFFAOYSA-N
InChI=1S/C13H12O7S2/c1-9-2-5-11(6-3-9)22(18,19)20-10-4-7-12(14)13(8-10)21(15,16)17/h2-8,14H,1H3,(H,15,16,17)

HIDE SMILES / InChI

Molecular Formula C13H12O7S2
Molecular Weight 344.36
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Sultosilic acid is a benzenesulfonate ester. Sultosilic acid has been shown to be a hypolipidaemic drug both in animal experiments and in human clinical studies, chemically unrelated to other such drugs. The compound is being developed as a human drug (Mimedran ®) and is formulated as the piperazine salt (A-585). The recommended daily dose is three times one tablet containing 500 mg of Sultosilic acid.

Approval Year

PubMed

PubMed

TitleDatePubMed
Treatment of type IIb familial combined hyperlipidemia with the combination pravastatin-piperazine sultosilate.
2004 Aug 2
Rationale for combination therapy with statin drugs in the treatment of dyslipidemia.
2005 Feb

Sample Use Guides

three times one tablet containing 500 mg of Sultosilic acid
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:51:04 GMT 2023
Edited
by admin
on Fri Dec 15 15:51:04 GMT 2023
Record UNII
62734PD6SM
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SULTOSILIC ACID
INN   MI   WHO-DD  
INN  
Official Name English
SULTOSILIC ACID [MI]
Common Name English
sultosilic acid [INN]
Common Name English
Sultosilic acid [WHO-DD]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29703
Created by admin on Fri Dec 15 15:51:04 GMT 2023 , Edited by admin on Fri Dec 15 15:51:04 GMT 2023
Code System Code Type Description
FDA UNII
62734PD6SM
Created by admin on Fri Dec 15 15:51:04 GMT 2023 , Edited by admin on Fri Dec 15 15:51:04 GMT 2023
PRIMARY
CAS
57775-26-5
Created by admin on Fri Dec 15 15:51:04 GMT 2023 , Edited by admin on Fri Dec 15 15:51:04 GMT 2023
PRIMARY
NCI_THESAURUS
C72085
Created by admin on Fri Dec 15 15:51:04 GMT 2023 , Edited by admin on Fri Dec 15 15:51:04 GMT 2023
PRIMARY
MESH
C024325
Created by admin on Fri Dec 15 15:51:04 GMT 2023 , Edited by admin on Fri Dec 15 15:51:04 GMT 2023
PRIMARY
MERCK INDEX
m10394
Created by admin on Fri Dec 15 15:51:04 GMT 2023 , Edited by admin on Fri Dec 15 15:51:04 GMT 2023
PRIMARY Merck Index
SMS_ID
100000082959
Created by admin on Fri Dec 15 15:51:04 GMT 2023 , Edited by admin on Fri Dec 15 15:51:04 GMT 2023
PRIMARY
ECHA (EC/EINECS)
260-943-0
Created by admin on Fri Dec 15 15:51:04 GMT 2023 , Edited by admin on Fri Dec 15 15:51:04 GMT 2023
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EPA CompTox
DTXSID50206459
Created by admin on Fri Dec 15 15:51:04 GMT 2023 , Edited by admin on Fri Dec 15 15:51:04 GMT 2023
PRIMARY
EVMPD
SUB10764MIG
Created by admin on Fri Dec 15 15:51:04 GMT 2023 , Edited by admin on Fri Dec 15 15:51:04 GMT 2023
PRIMARY
PUBCHEM
68775
Created by admin on Fri Dec 15 15:51:04 GMT 2023 , Edited by admin on Fri Dec 15 15:51:04 GMT 2023
PRIMARY
DRUG CENTRAL
2542
Created by admin on Fri Dec 15 15:51:04 GMT 2023 , Edited by admin on Fri Dec 15 15:51:04 GMT 2023
PRIMARY
ChEMBL
CHEMBL2105492
Created by admin on Fri Dec 15 15:51:04 GMT 2023 , Edited by admin on Fri Dec 15 15:51:04 GMT 2023
PRIMARY
INN
4034
Created by admin on Fri Dec 15 15:51:04 GMT 2023 , Edited by admin on Fri Dec 15 15:51:04 GMT 2023
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
Related Record Type Details
ACTIVE MOIETY