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Details

Stereochemistry ABSOLUTE
Molecular Formula C32H48N4O8.ClH
Molecular Weight 653.206
Optical Activity UNSPECIFIED
Defined Stereocenters 6 / 6
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ALVESPIMYCIN HYDROCHLORIDE

SMILES

Cl.CO[C@H]1C[C@H](C)CC2=C(NCCN(C)C)C(=O)C=C(NC(=O)\C(C)=C\C=C[C@H](OC)[C@@H](OC(N)=O)\C(C)=C\[C@H](C)[C@H]1O)C2=O

InChI

InChIKey=DFSYBWLNYPEFJK-IHLRWNDRSA-N
InChI=1S/C32H48N4O8.ClH/c1-18-14-22-27(34-12-13-36(5)6)24(37)17-23(29(22)39)35-31(40)19(2)10-9-11-25(42-7)30(44-32(33)41)21(4)16-20(3)28(38)26(15-18)43-8;/h9-11,16-18,20,25-26,28,30,34,38H,12-15H2,1-8H3,(H2,33,41)(H,35,40);1H/b11-9-,19-10+,21-16+;/t18-,20+,25+,26+,28-,30+;/m1./s1

HIDE SMILES / InChI
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C32H48N4O8
Molecular Weight 616.7455
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 6 / 6
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Alvespimycin (17-desmethoxy-17-N,N-dimethylaminoethylamino-geldanamycin) (17-DMAG; NSC 707545) is an inhibitor of the molecular chaperone heat shock protein HSP90. Alvespimycin is a derivative of antineoplastic benzoquinone antibiotic geldanamycin. Alvespimycin binds to HSP90, a chaperone protein that aids in the assembly, maturation and folding of proteins. Subsequently, the function of Hsp90 is inhibited, leading to the degradation and depletion of its client proteins such as kinases and transcription factors involved with cell cycle regulation and signal transduction. Alvespimycin was studied in clinical trials for the treatment of solid tumors and hematologic malignancies however its development was discontinued.

CNS Activity

CNS Active
3913
Curator's Comment: Alvespimycin (17-DMAG) is brain penetrant and CNS active in animals. No human data available.

Originator

Approval Year

Unknown
139594
Targets

Targets

Primary TargetPharmacologyConditionPotency
Inhibitor
8297
 62.0 nM [EC50]
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Phase II
1132
Unknown

Approved Use

Unknown
Primary
Phase I
428
Unknown

Approved Use

Unknown
Doses

Doses

DosePopulationAdverse events​
106 mg/m2 1 times / week multiple, intravenous
Highest studied dose
Dose: 106 mg/m2, 1 times / week
Route: intravenous
Route: multiple
Dose: 106 mg/m2, 1 times / week
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
unhealthy, ADULT
n = 4
Health Status: unhealthy
Condition: cancer
Age Group: ADULT
Sex: M+F
Food Status: UNKNOWN
Population Size: 4
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
DLT: Acidosis, Nausea...
Other AEs: Blood creatinine increased...
Dose limiting toxicities:
Acidosis (grade 3, 25%)
Nausea (grade 2, 25%)
Hyponatremia (grade 3, 25%)
Diarrhea (grade 3, 25%)
Anorexia (grade 2, 25%)
Dehydration (grade 3, 25%)
Vomiting (grade 2, 25%)
AST increased (grade 4, 25%)
Acute hypotension (grade 4, 25%)
Fatigue (grade 3, 25%)
Fever (grade 2, 25%)
Hypoalbuminemia (grade 3, 25%)
Acute renal failure (grade 5, 25%)
Other AEs:
Blood creatinine increased (grade 3, 25%)
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
24 mg/m2 2 times / week multiple, intravenous
MTD
Dose: 24 mg/m2, 2 times / week
Route: intravenous
Route: multiple
Dose: 24 mg/m2, 2 times / week
Sources:
https://pubmed.ncbi.nlm.nih.gov/20111068
Page: p.702
unhealthy, ADULT
n = 11
Health Status: unhealthy
Condition: acute myeloid leukemia
Age Group: ADULT
Sex: M+F
Food Status: UNKNOWN
Population Size: 11
Sources:
https://pubmed.ncbi.nlm.nih.gov/20111068
Page: p.702
DLT: Diarrhea...
Dose limiting toxicities:
Diarrhea (grade 3-4, 9%)
Sources:
https://pubmed.ncbi.nlm.nih.gov/20111068
Page: p.702
80 mg/m2 1 times / week multiple, intravenous
MTD
Dose: 80 mg/m2, 1 times / week
Route: intravenous
Route: multiple
Dose: 80 mg/m2, 1 times / week
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.6
unhealthy, ADULT
n = 8
Health Status: unhealthy
Condition: cancer
Age Group: ADULT
Sex: M+F
Food Status: UNKNOWN
Population Size: 8
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.6
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.6
32 mg/m2 2 times / week multiple, intravenous
Studied dose
Dose: 32 mg/m2, 2 times / week
Route: intravenous
Route: multiple
Dose: 32 mg/m2, 2 times / week
Sources:
https://pubmed.ncbi.nlm.nih.gov/20111068
Page: p.701, 702
unhealthy, ADULT
n = 2
Health Status: unhealthy
Condition: acute myeloid leukemia
Age Group: ADULT
Sex: M+F
Food Status: UNKNOWN
Population Size: 2
Sources:
https://pubmed.ncbi.nlm.nih.gov/20111068
Page: p.701, 702
DLT: Acute myocardial infarction, Cardiac ischemia...
Dose limiting toxicities:
Acute myocardial infarction (grade 5, 50%)
Cardiac ischemia (grade 3-4, 50%)
Sources:
https://pubmed.ncbi.nlm.nih.gov/20111068
Page: p.701, 702
AEs

AEs

AESignificanceDosePopulation
Anorexia grade 2, 25%
DLT, Disc. AE
106 mg/m2 1 times / week multiple, intravenous
Highest studied dose
Dose: 106 mg/m2, 1 times / week
Route: intravenous
Route: multiple
Dose: 106 mg/m2, 1 times / week
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
unhealthy, ADULT
n = 4
Health Status: unhealthy
Condition: cancer
Age Group: ADULT
Sex: M+F
Food Status: UNKNOWN
Population Size: 4
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
Fever grade 2, 25%
DLT, Disc. AE
106 mg/m2 1 times / week multiple, intravenous
Highest studied dose
Dose: 106 mg/m2, 1 times / week
Route: intravenous
Route: multiple
Dose: 106 mg/m2, 1 times / week
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
unhealthy, ADULT
n = 4
Health Status: unhealthy
Condition: cancer
Age Group: ADULT
Sex: M+F
Food Status: UNKNOWN
Population Size: 4
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
Nausea grade 2, 25%
DLT, Disc. AE
106 mg/m2 1 times / week multiple, intravenous
Highest studied dose
Dose: 106 mg/m2, 1 times / week
Route: intravenous
Route: multiple
Dose: 106 mg/m2, 1 times / week
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
unhealthy, ADULT
n = 4
Health Status: unhealthy
Condition: cancer
Age Group: ADULT
Sex: M+F
Food Status: UNKNOWN
Population Size: 4
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
Vomiting grade 2, 25%
DLT, Disc. AE
106 mg/m2 1 times / week multiple, intravenous
Highest studied dose
Dose: 106 mg/m2, 1 times / week
Route: intravenous
Route: multiple
Dose: 106 mg/m2, 1 times / week
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
unhealthy, ADULT
n = 4
Health Status: unhealthy
Condition: cancer
Age Group: ADULT
Sex: M+F
Food Status: UNKNOWN
Population Size: 4
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
Blood creatinine increased grade 3, 25%
106 mg/m2 1 times / week multiple, intravenous
Highest studied dose
Dose: 106 mg/m2, 1 times / week
Route: intravenous
Route: multiple
Dose: 106 mg/m2, 1 times / week
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
unhealthy, ADULT
n = 4
Health Status: unhealthy
Condition: cancer
Age Group: ADULT
Sex: M+F
Food Status: UNKNOWN
Population Size: 4
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
Fatigue grade 3, 25%
DLT
106 mg/m2 1 times / week multiple, intravenous
Highest studied dose
Dose: 106 mg/m2, 1 times / week
Route: intravenous
Route: multiple
Dose: 106 mg/m2, 1 times / week
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
unhealthy, ADULT
n = 4
Health Status: unhealthy
Condition: cancer
Age Group: ADULT
Sex: M+F
Food Status: UNKNOWN
Population Size: 4
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
Hypoalbuminemia grade 3, 25%
DLT
106 mg/m2 1 times / week multiple, intravenous
Highest studied dose
Dose: 106 mg/m2, 1 times / week
Route: intravenous
Route: multiple
Dose: 106 mg/m2, 1 times / week
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
unhealthy, ADULT
n = 4
Health Status: unhealthy
Condition: cancer
Age Group: ADULT
Sex: M+F
Food Status: UNKNOWN
Population Size: 4
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
Acidosis grade 3, 25%
DLT, Disc. AE
106 mg/m2 1 times / week multiple, intravenous
Highest studied dose
Dose: 106 mg/m2, 1 times / week
Route: intravenous
Route: multiple
Dose: 106 mg/m2, 1 times / week
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
unhealthy, ADULT
n = 4
Health Status: unhealthy
Condition: cancer
Age Group: ADULT
Sex: M+F
Food Status: UNKNOWN
Population Size: 4
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
Dehydration grade 3, 25%
DLT, Disc. AE
106 mg/m2 1 times / week multiple, intravenous
Highest studied dose
Dose: 106 mg/m2, 1 times / week
Route: intravenous
Route: multiple
Dose: 106 mg/m2, 1 times / week
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
unhealthy, ADULT
n = 4
Health Status: unhealthy
Condition: cancer
Age Group: ADULT
Sex: M+F
Food Status: UNKNOWN
Population Size: 4
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
Diarrhea grade 3, 25%
DLT, Disc. AE
106 mg/m2 1 times / week multiple, intravenous
Highest studied dose
Dose: 106 mg/m2, 1 times / week
Route: intravenous
Route: multiple
Dose: 106 mg/m2, 1 times / week
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
unhealthy, ADULT
n = 4
Health Status: unhealthy
Condition: cancer
Age Group: ADULT
Sex: M+F
Food Status: UNKNOWN
Population Size: 4
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
Hyponatremia grade 3, 25%
DLT, Disc. AE
106 mg/m2 1 times / week multiple, intravenous
Highest studied dose
Dose: 106 mg/m2, 1 times / week
Route: intravenous
Route: multiple
Dose: 106 mg/m2, 1 times / week
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
unhealthy, ADULT
n = 4
Health Status: unhealthy
Condition: cancer
Age Group: ADULT
Sex: M+F
Food Status: UNKNOWN
Population Size: 4
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
AST increased grade 4, 25%
DLT, Disc. AE
106 mg/m2 1 times / week multiple, intravenous
Highest studied dose
Dose: 106 mg/m2, 1 times / week
Route: intravenous
Route: multiple
Dose: 106 mg/m2, 1 times / week
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
unhealthy, ADULT
n = 4
Health Status: unhealthy
Condition: cancer
Age Group: ADULT
Sex: M+F
Food Status: UNKNOWN
Population Size: 4
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
Acute hypotension grade 4, 25%
DLT, Disc. AE
106 mg/m2 1 times / week multiple, intravenous
Highest studied dose
Dose: 106 mg/m2, 1 times / week
Route: intravenous
Route: multiple
Dose: 106 mg/m2, 1 times / week
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
unhealthy, ADULT
n = 4
Health Status: unhealthy
Condition: cancer
Age Group: ADULT
Sex: M+F
Food Status: UNKNOWN
Population Size: 4
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
Acute renal failure grade 5, 25%
DLT, Disc. AE
106 mg/m2 1 times / week multiple, intravenous
Highest studied dose
Dose: 106 mg/m2, 1 times / week
Route: intravenous
Route: multiple
Dose: 106 mg/m2, 1 times / week
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
unhealthy, ADULT
n = 4
Health Status: unhealthy
Condition: cancer
Age Group: ADULT
Sex: M+F
Food Status: UNKNOWN
Population Size: 4
Sources:
https://pubmed.ncbi.nlm.nih.gov/21278242
Page: p.5, 6
Diarrhea grade 3-4, 9%
DLT
24 mg/m2 2 times / week multiple, intravenous
MTD
Dose: 24 mg/m2, 2 times / week
Route: intravenous
Route: multiple
Dose: 24 mg/m2, 2 times / week
Sources:
https://pubmed.ncbi.nlm.nih.gov/20111068
Page: p.702
unhealthy, ADULT
n = 11
Health Status: unhealthy
Condition: acute myeloid leukemia
Age Group: ADULT
Sex: M+F
Food Status: UNKNOWN
Population Size: 11
Sources:
https://pubmed.ncbi.nlm.nih.gov/20111068
Page: p.702
Cardiac ischemia grade 3-4, 50%
DLT
32 mg/m2 2 times / week multiple, intravenous
Studied dose
Dose: 32 mg/m2, 2 times / week
Route: intravenous
Route: multiple
Dose: 32 mg/m2, 2 times / week
Sources:
https://pubmed.ncbi.nlm.nih.gov/20111068
Page: p.701, 702
unhealthy, ADULT
n = 2
Health Status: unhealthy
Condition: acute myeloid leukemia
Age Group: ADULT
Sex: M+F
Food Status: UNKNOWN
Population Size: 2
Sources:
https://pubmed.ncbi.nlm.nih.gov/20111068
Page: p.701, 702
Acute myocardial infarction grade 5, 50%
DLT, Disc. AE
32 mg/m2 2 times / week multiple, intravenous
Studied dose
Dose: 32 mg/m2, 2 times / week
Route: intravenous
Route: multiple
Dose: 32 mg/m2, 2 times / week
Sources:
https://pubmed.ncbi.nlm.nih.gov/20111068
Page: p.701, 702
unhealthy, ADULT
n = 2
Health Status: unhealthy
Condition: acute myeloid leukemia
Age Group: ADULT
Sex: M+F
Food Status: UNKNOWN
Population Size: 2
Sources:
https://pubmed.ncbi.nlm.nih.gov/20111068
Page: p.701, 702
Sourcing

Sourcing

Vendor/AggregatorIDURL
AK Scientific, Inc. (AKSCI)
X8446
http://www.aksci.com/item_detail.php?cat=X8446
Achemtek
0101-002334
http://www.achemtek.com/467214-20-6
Acorn PharmaTech
ACN-046374
http://www.acornpharmatech.com/
Active Biopharma
ABP000223
http://www.activebiopharma.com/150270-08-9
Active Biopharma
ABP000584
http://www.activebiopharma.com/467214-21-7
Aurora Fine Chemicals LLC
A13.105.467
http://online.aurorafinechemicals.com/info?ID=A13.105.467
Aurum Pharmatech LLC
W-5374
http://www.Aurumpharmatech.com/Product/ProductDetails/W_5374
AvaChem Scientific
6006
https://www.avachem.com/productSearch.asp?6006
BOC Sciences
150270-08-9
https://www.bocsci.com/17-dimethylaminoethylamino-17-demethoxygeldanamycin-cas-150270-08-9-item-122708.html
BioCrick
BCC1346
http://www.biocrick.com/Alvespimycin-BCC1346.html
Chem Scene
CS-0912
http://www.chemscene.com/467214-20-6.html
ChemMol
99046992
http://www.chemmol.com/chemmol/99046992.html
ChemShuttle
159942
http://www.chemshuttle.com/catalogsearch/result/?q=467214-20-6&cat=
Chemspace
CSSB00116207116
https://chem-space.com/CSSB00116207116
DC Chemicals
DC36820
http://www.dcchemicals.com//product_show-Alvespimycin.html
Excenen
EX-A1103
http://www.excenen.com/searchresultlist.php?id=467214-20-6
Hairui
HR116175
http://www.hairuichem.com/en/product/467214-20-6.html
Matrix Scientific
89480
https://www.matrixscientific.com/089480.html
MedChem Express
HY-10389
https://www.medchemexpress.com/alvespimycin.html
MolPort
MolPort-006-666-027
https://www.molport.com/shop/molecule-link/MolPort-006-666-027
MuseChem
I003618
https://www.musechem.com/product/I003618.html
MuseChem
M097169
https://www.musechem.com/product/M097169.html
OChem
26905
http://www.ocheminc.com/index.php?act=psearch&pid=214D206
Oakwood
M03709
http://www.oakwoodchemical.com/ProductsList.aspx?CategoryID=-2&txtSearch=128507&ExtHyperLink=1
Smolecule
S518217
http://www.smolecule.com/products/s518217
THE BioTek
bt-258596
https://www.thebiotek.com/product/inhibitors/bt-258596
abcr GmbH
AB200576
http://www.abcr.com/shop/en/AB200576
eNovation Chemicals
D567341
https://www.enovationchem.com/ProductDetails.asp?ProductID=D567341
eNovation Chemicals
Y1012794
https://www.enovationchem.com/ProductDetails.asp?ProductID=Y1012794
PubMed

PubMed

TitleDatePubMed
Evidence that intrathecal morphine-3-glucuronide may cause pain enhancement via toll-like receptor 4/MD-2 and interleukin-1beta.
2010 Jan 20
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies.
2011 Jul
Differential protein stability and ALK inhibitor sensitivity of EML4-ALK fusion variants.
2012 Sep 1
Patents

Patents

20050026894
3

Sample Use Guides

In Vivo Use Guide
Phase 1 study. Patients with advanced acute myeloid leukemia (AML) received escalating doses of intravenous alvespimycin (8-32 mg/m(2)), twice weekly, for 2 of 3 weeks. Alvespimycin was well tolerated; the maximum-tolerated dose was 24 mg/m(2) twice weekly. Common toxicities included neutropenic fever, fatigue, nausea and diarrhea. Cardiac DLTs occurred at 32 mg/m(2) (elevated troponin and myocardial infarction). Pharmacokinetics revealed linear increases in C(max) and area under the curve (AUC) from 8 to 32 mg/m(2) and minor accumulation upon repeated doses. Recommended phase 2 dose is 24 mg/m(2).
Route of Administration: Intravenous
In Vitro Use Guide
One hepatic cell line (L02) and two HCC cell lines (Huh7 and HepG2) were heated at 42 °C for 0, 0.5 or 4 h with or without 100 nM alvespimycin (17-DMAG).
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:52:51 GMT 2023
Edited
by admin
on Fri Dec 15 15:52:51 GMT 2023
Record UNII
612K359T69
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ALVESPIMYCIN HYDROCHLORIDE
USAN   WHO-DD  
USAN  
Official Name English
KOS-1022
Code English
ALVESPIMYCIN HYDROCHLORIDE [USAN]
Common Name English
BMS-826476
Code English
(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-((2-(DIMETHYLAMINO)ETHYL)AMINO)-13-HYDROXY-8,14-DIMETHOXY-4,10,12,16-TETRAMETHYL-3,20,22-TRIOXO-2-AZABICYCLO(16.3.1)DOCOSA-1(21),4,6,10,18-PENTAEN-9-YL CARBAMATE HYDROCHLORIDE
Common Name English
ALVESPIMYCIN HCL
Common Name English
Alvespimycin hydrochloride [WHO-DD]
Common Name English
GELDANAMYCIN, 17-DEMETHOXY-17-((2-(DIMETHYLAMINO)ETHYL)AMINO)-, MONOHYDROCHLORIDE
Common Name English
17-DMAG HCL
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C2516
Created by admin on Fri Dec 15 15:52:51 GMT 2023 , Edited by admin on Fri Dec 15 15:52:51 GMT 2023
Code System Code Type Description
CAS
467214-21-7
Created by admin on Fri Dec 15 15:52:51 GMT 2023 , Edited by admin on Fri Dec 15 15:52:51 GMT 2023
PRIMARY
PUBCHEM
9852573
Created by admin on Fri Dec 15 15:52:51 GMT 2023 , Edited by admin on Fri Dec 15 15:52:51 GMT 2023
PRIMARY
FDA UNII
612K359T69
Created by admin on Fri Dec 15 15:52:51 GMT 2023 , Edited by admin on Fri Dec 15 15:52:51 GMT 2023
PRIMARY
USAN
WW-59
Created by admin on Fri Dec 15 15:52:51 GMT 2023 , Edited by admin on Fri Dec 15 15:52:51 GMT 2023
PRIMARY
ChEMBL
CHEMBL383824
Created by admin on Fri Dec 15 15:52:51 GMT 2023 , Edited by admin on Fri Dec 15 15:52:51 GMT 2023
PRIMARY
EPA CompTox
DTXSID40431773
Created by admin on Fri Dec 15 15:52:51 GMT 2023 , Edited by admin on Fri Dec 15 15:52:51 GMT 2023
PRIMARY
NCI_THESAURUS
C76665
Created by admin on Fri Dec 15 15:52:51 GMT 2023 , Edited by admin on Fri Dec 15 15:52:51 GMT 2023
PRIMARY
DRUG BANK
DBSALT002385
Created by admin on Fri Dec 15 15:52:51 GMT 2023 , Edited by admin on Fri Dec 15 15:52:51 GMT 2023
PRIMARY
SMS_ID
300000042545
Created by admin on Fri Dec 15 15:52:51 GMT 2023 , Edited by admin on Fri Dec 15 15:52:51 GMT 2023
PRIMARY
Related Record Type Details
Structure of ALVESPIMYCIN
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of ALVESPIMYCIN
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