MINDODILOL

Details

Stereochemistry	RACEMIC
Molecular Formula	C23H28N2O3
Molecular Weight	380.48
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(COC1=CC=CC2=C1C=CN2)CN3CCC(COC4=CC=CC=C4)CC3

InChI

InChIKey=ARFNSMYWLYZEPU-UHFFFAOYSA-N

InChI=1S/C23H28N2O3/c26-19(17-28-23-8-4-7-22-21(23)9-12-24-22)15-25-13-10-18(11-14-25)16-27-20-5-2-1-3-6-20/h1-9,12,18-19,24,26H,10-11,13-17H2

HIDE SMILES / InChI

Molecular Formula	C23H28N2O3
Molecular Weight	380.48
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6119183

Mindodilol (also known as BM 12,434) was investigated as a beta-adrenoceptor-blocking agent. This drug was potentially useful for the treatment of both coronary heart disease and of arterial hypertension. However, information about the further development of this drug is not available.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Adrenergic receptor beta 89 Target ID: CHEMBL2094118 Sources: https://www.ncbi.nlm.nih.gov/pubmed/6119183	Antagonist 2849

PubMed

Title	Date	PubMed
BM 12.434, a novel compound with vasodilating and beta-adrenoceptor-blocking activities.	1981-12	6119183

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:37:51 GMT 2025` Edited by `admin` on `Mon Mar 31 18:37:51 GMT 2025`
Record UNII	5VI1D4HYXC
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BM-12434

Preferred Name

English

MINDODILOL

Official Name

English

(±)-.ALPHA.-((INDOL-4-YLOXY)METHYL)-4-(PHENOXYMETHYL)-1-PIPERIDINEETHANOL

Systematic Name

English

mindodilol [INN]

Common Name

English

1-PIPERIDINEETHANOL, .ALPHA.-((1H-INDOL-4-YLOXY)METHYL)-4-(PHENOXYMETHYL)-

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29707