Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C27H44O2 |
| Molecular Weight | 400.6371 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 7 / 7 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]1(CC(=O)C2=C3CC[C@@]4([H])C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)C
InChI
InChIKey=LINVVMHRTUSXHL-GGVPDPBRSA-N
InChI=1S/C27H44O2/c1-17(2)7-6-8-18(3)23-16-24(29)25-21-10-9-19-15-20(28)11-13-26(19,4)22(21)12-14-27(23,25)5/h17-20,22-23,28H,6-16H2,1-5H3/t18-,19+,20+,22+,23-,26+,27-/m1/s1
| Molecular Formula | C27H44O2 |
| Molecular Weight | 400.6371 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 7 / 7 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Colestolone (5 alpha-cholest-8(14)-en-3 beta-ol-15-one) is an inhibitor of sterol biosynthesis. The compound reduces the level of 3-hydroxy-3-methylglutaryl coenzyme A reductive activity in cultured mammalian cells. In nonhuman primates, the compound decreases the levels of total serum cholesterol and low-density lipoprotein and increases the percentage of total cholesterol associated with high-density lipoprotein.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:16:21 GMT 2023
by
admin
on
Fri Dec 15 15:16:21 GMT 2023
|
| Record UNII |
5P8396T5XF
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
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Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C29703
Created by
admin on Fri Dec 15 15:16:22 GMT 2023 , Edited by admin on Fri Dec 15 15:16:22 GMT 2023
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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61829
Created by
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C81532
Created by
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SUB06796MIG
Created by
admin on Fri Dec 15 15:16:22 GMT 2023 , Edited by admin on Fri Dec 15 15:16:22 GMT 2023
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Colestolone
Created by
admin on Fri Dec 15 15:16:22 GMT 2023 , Edited by admin on Fri Dec 15 15:16:22 GMT 2023
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CHEMBL2104586
Created by
admin on Fri Dec 15 15:16:22 GMT 2023 , Edited by admin on Fri Dec 15 15:16:22 GMT 2023
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DTXSID6046212
Created by
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50673-97-7
Created by
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6245
Created by
admin on Fri Dec 15 15:16:22 GMT 2023 , Edited by admin on Fri Dec 15 15:16:22 GMT 2023
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100000084244
Created by
admin on Fri Dec 15 15:16:22 GMT 2023 , Edited by admin on Fri Dec 15 15:16:22 GMT 2023
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5P8396T5XF
Created by
admin on Fri Dec 15 15:16:22 GMT 2023 , Edited by admin on Fri Dec 15 15:16:22 GMT 2023
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10046567
Created by
admin on Fri Dec 15 15:16:22 GMT 2023 , Edited by admin on Fri Dec 15 15:16:22 GMT 2023
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PRIMARY | |||
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Z-15
Created by
admin on Fri Dec 15 15:16:22 GMT 2023 , Edited by admin on Fri Dec 15 15:16:22 GMT 2023
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PRIMARY |
| Related Record | Type | Details | ||
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ACTIVE MOIETY |
