PARGOLOL

Details

Stereochemistry	RACEMIC
Molecular Formula	C16H23NO3
Molecular Weight	277.3587
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)(C)NCC(O)COC1=C(OCC#C)C=CC=C1

InChI

InChIKey=UFNAECVCKNHAKN-UHFFFAOYSA-N

InChI=1S/C16H23NO3/c1-5-10-19-14-8-6-7-9-15(14)20-12-13(18)11-17-16(2,3)4/h1,6-9,13,17-18H,10-12H2,2-4H3

HIDE SMILES / InChI

Molecular Formula	C16H23NO3
Molecular Weight	277.3587
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6110251

Pargolol (also Kö 1400) is a beta-adrenergic receptor blocking agent that was developed as an antiarrhythmic agent. However, information about the further development of this drug is not available.

Approval Year

PubMed

Title	Date	PubMed
Antiarrhythmic effect of oxprenolol on halothane-epinephrine and coronary ligation induced ventricular arrhythmias in beagle dogs.	1978 Aug	32416

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:37:26 GMT 2023` Edited by `admin` on `Fri Dec 15 16:37:26 GMT 2023`
Record UNII	5OPO851W5L
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PARGOLOL

Official Name

English

2-PROPANOL, 1-((1,1-DIMETHYLETHYL)AMINO)-3-(2-(2-PROPYN-1-YLOXY)PHENOXY)-

Systematic Name

English

1-(TERT-BUTYLAMINO)-3-(O-(2-PROPYNYLOXY)PHENOXY)-2-PROPANOL

Common Name

English

pargolol [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29576