PARGOLOL

Details

Stereochemistry	RACEMIC
Molecular Formula	C16H23NO3
Molecular Weight	277.3587
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)(C)NCC(O)COC1=C(OCC#C)C=CC=C1

InChI

InChIKey=UFNAECVCKNHAKN-UHFFFAOYSA-N

InChI=1S/C16H23NO3/c1-5-10-19-14-8-6-7-9-15(14)20-12-13(18)11-17-16(2,3)4/h1,6-9,13,17-18H,10-12H2,2-4H3

HIDE SMILES / InChI

Molecular Formula	C16H23NO3
Molecular Weight	277.3587
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6110251

Pargolol (also Kö 1400) is a beta-adrenergic receptor blocking agent that was developed as an antiarrhythmic agent. However, information about the further development of this drug is not available.

Approval Year

PubMed

Title	Date	PubMed
[Experimental anti-arrhythmic effects of a new beta-adrenergic receptor blocking agent, dl-l-(tert. butylamino)-3-[(2-propinyloxy)phenoxy]2-propanol hydrochloride (dl Kö 1400-Cl)].	1976 Jul	11153

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:37:26 UTC 2023` Edited by `admin` on `Fri Dec 15 16:37:26 UTC 2023`
Record UNII	5OPO851W5L
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PARGOLOL

Official Name

English

2-PROPANOL, 1-((1,1-DIMETHYLETHYL)AMINO)-3-(2-(2-PROPYN-1-YLOXY)PHENOXY)-

Systematic Name

English

1-(TERT-BUTYLAMINO)-3-(O-(2-PROPYNYLOXY)PHENOXY)-2-PROPANOL

Common Name

English

pargolol [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29576