U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 15:18:15 GMT 2023
Edited
by admin
on Sat Dec 16 15:18:15 GMT 2023
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
5L54H526NG
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-2
Common Name English
BMPR-II
Common Name English
PPH1
Common Name English
BMPR-2
Common Name English
Code System Code Type Description
UNIPROT
Q13873
Created by admin on Sat Dec 16 15:18:15 GMT 2023 , Edited by admin on Sat Dec 16 15:18:15 GMT 2023
PRIMARY
FDA UNII
5L54H526NG
Created by admin on Sat Dec 16 15:18:15 GMT 2023 , Edited by admin on Sat Dec 16 15:18:15 GMT 2023
PRIMARY
From To
1_8 1_40
1_34 1_58
1_68 1_91
1_73 1_90
1_92 1_97
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_29
N 1_84
N 1_100
Related Record Type Details
AGONIST -> TARGET
Able to bind to BMPR2 without BMPR1 however, the affinity significantly increases in the presence of both receptors. BMPR1 is transphosphorylated via BMPR2 which induces downstream signalling within the cell, affecting transcription.
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT CHEMICAL