Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 15:02:26 GMT 2023
by
admin
on
Sat Dec 16 15:02:26 GMT 2023
|
| Protein Type | GROWTH FACTOR |
| Protein Sub Type | |
| Sequence Origin | HUMAN |
| Sequence Type | COMPLETE |
| Record UNII |
08RQ4CQ601
|
| Record Status |
Validated (UNII)
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| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
EU-Orphan Drug |
EU/3/14/1348
Created by
admin on Sat Dec 16 15:02:26 GMT 2023 , Edited by admin on Sat Dec 16 15:02:26 GMT 2023
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FDA ORPHAN DRUG |
520216
Created by
admin on Sat Dec 16 15:02:26 GMT 2023 , Edited by admin on Sat Dec 16 15:02:26 GMT 2023
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
C131018
Created by
admin on Sat Dec 16 15:02:26 GMT 2023 , Edited by admin on Sat Dec 16 15:02:26 GMT 2023
|
PRIMARY | |||
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08RQ4CQ601
Created by
admin on Sat Dec 16 15:02:26 GMT 2023 , Edited by admin on Sat Dec 16 15:02:26 GMT 2023
|
PRIMARY | |||
|
Bone_morphogenetic_protein_4
Created by
admin on Sat Dec 16 15:02:26 GMT 2023 , Edited by admin on Sat Dec 16 15:02:26 GMT 2023
|
PRIMARY |
| From | To |
|---|---|
| 1_16 | 1_81 |
| 1_80 | 2_80 |
| 1_45 | 1_113 |
| 1_49 | 1_115 |
| 2_16 | 2_81 |
| 2_45 | 2_113 |
| 2_49 | 2_115 |
| Glycosylation Type | MAMMALIAN |
| Glycosylation Link Type | Site |
|---|---|
| N | 1_58 |
| N | 1_73 |
| N | 2_58 |
| N | 2_73 |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
TARGET -> AGONIST |
Binds to 2 different types of serine-threonine kinase receptors known as BMPR1 and BMPR2.
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TARGET -> AGONIST |
Able to bind to BMPR2 without BMPR1 however, the affinity significantly increases in the presence of both receptors. BMPR1 is transphosphorylated via BMPR2 which induces downstream signalling within the cell, affecting transcription.
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| Related Record | Type | Details | ||
|---|---|---|---|---|
|
ACTIVE MOIETY |
| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| Molecular Formula | CHEMICAL |
|
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| MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
|