Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 15:23:56 UTC 2023
by
admin
on
Sat Dec 16 15:23:56 UTC 2023
|
| Protein Type | TRANSCRIPTION FACTOR |
| Protein Sub Type | |
| Sequence Origin | HUMAN |
| Sequence Type | COMPLETE |
| Record UNII |
5GAV4KY0LX
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
Q04206
Created by
admin on Sat Dec 16 15:23:56 UTC 2023 , Edited by admin on Sat Dec 16 15:23:56 UTC 2023
|
PRIMARY | |||
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P19838
Created by
admin on Sat Dec 16 15:23:56 UTC 2023 , Edited by admin on Sat Dec 16 15:23:56 UTC 2023
|
PRIMARY | |||
|
5GAV4KY0LX
Created by
admin on Sat Dec 16 15:23:56 UTC 2023 , Edited by admin on Sat Dec 16 15:23:56 UTC 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
INHIBITOR -> TARGET |
Helenalin selectively alkylates p65 subunit at
Cys38 [27, 63]. Formation of this covalent bond sterically
prevents the p50/p65 heterodimer from binding to DNA and therefore inhibits its transcriptional activation.
|
| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
|