| Stereochemistry | ABSOLUTE |
| Molecular Formula | C23H22Cl2F3NO3 |
| Molecular Weight | 488.327 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]([C@@H](C)C(F)(F)F)(C(=O)NC1=CC(=CC=C1Cl)[C@@H](CC(O)=O)C2CC2)C3=CC=C(Cl)C=C3
InChI
InChIKey=NCRMKIWHFXSBGZ-CNBXIYLPSA-N
InChI=1S/C23H22Cl2F3NO3/c1-12(23(26,27)28)21(14-4-7-16(24)8-5-14)22(32)29-19-10-15(6-9-18(19)25)17(11-20(30)31)13-2-3-13/h4-10,12-13,17,21H,2-3,11H2,1H3,(H,29,32)(H,30,31)/t12-,17+,21+/m1/s1
| Molecular Formula | C23H22Cl2F3NO3 |
| Molecular Weight | 488.327 |
| Charge | 0 |
| Count |
MOL RATIO
1 MOL RATIO (average) |
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
|
|
TARGET -> ACTIVATOR |
NO- and heme-independent activator of sGC
EC50
30 NANOMOLAR (average) |
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