Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C15H22N2O2.CH4O3S |
| Molecular Weight | 358.453 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CS(O)(=O)=O.CN1CCCC2=C1C(OC[C@@H]3CNCCO3)=CC=C2
InChI
InChIKey=RSEKRLGWBUABQM-ZOWNYOTGSA-N
InChI=1S/C15H22N2O2.CH4O3S/c1-17-8-3-5-12-4-2-6-14(15(12)17)19-11-13-10-16-7-9-18-13;1-5(2,3)4/h2,4,6,13,16H,3,5,7-11H2,1H3;1H3,(H,2,3,4)/t13-;/m0./s1
| Molecular Formula | C15H22N2O2 |
| Molecular Weight | 262.3474 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
| Molecular Formula | CH4O3S |
| Molecular Weight | 96.106 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Dabelotine is a cognitive-enhancing drug, developed by Servier. The drug has been shown to improve some aspects of cognitive processes, such as attention, curiosity, motivation, acquisition, and recall of memory. Dabelotine has also been shown to reduce the effect of an anticholinergic drug such as scopolamine. The drug increases the in vitro K+-induced norepinephrine release in rodent cerebral slices, and have no effect on noradrenergic and cholinergic receptor binding sites. Dabelotine was investigated in phase 2 clinical trials for the treatment of dementia, where it was demonstrated that 50-mg and 100-mg doses produced an improvement in reaction time and performance in memory tasks.
CNS Activity
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 23:42:00 GMT 2025
by
admin
on
Mon Mar 31 23:42:00 GMT 2025
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| Record UNII |
596JG0W99X
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| Record Status |
Validated (UNII)
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| Record Version |
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-
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596JG0W99X
Created by
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132958
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DTXSID30934642
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admin on Mon Mar 31 23:42:00 GMT 2025 , Edited by admin on Mon Mar 31 23:42:00 GMT 2025
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152985-36-9
Created by
admin on Mon Mar 31 23:42:00 GMT 2025 , Edited by admin on Mon Mar 31 23:42:00 GMT 2025
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