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Details

Stereochemistry ACHIRAL
Molecular Formula C19H16ClNO4
Molecular Weight 357.788
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of RILOPIROX

SMILES

CC1=CC(=O)N(O)C(COC2=CC=C(OC3=CC=C(Cl)C=C3)C=C2)=C1

InChI

InChIKey=UDYUIWXQUBNDHC-UHFFFAOYSA-N
InChI=1S/C19H16ClNO4/c1-13-10-15(21(23)19(22)11-13)12-24-16-6-8-18(9-7-16)25-17-4-2-14(20)3-5-17/h2-11,23H,12H2,1H3

HIDE SMILES / InChI

Molecular Formula C19H16ClNO4
Molecular Weight 357.788
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Rilopirox (HOE 351) is a fungicidal antimycotic that was developed as an intravaginal antifungal with a long skin retention time and a strong killing effect on pathogenic yeasts. Its very low water solubility makes rilopirox a good candidate for an intravaginal antifungal. Potential applications may be in mucosal candida infections, tinea versicolor and seborrheic dermatitis. In addition, it has been suggested that rilopirox could be effective against oropharyngeal Candida infections, for example in AIDS patients. There is no information on current development of rilopirox.

Originator

Approval Year

PubMed

Patents

Substance Class Chemical
Record UNII
595T4D0KQ3
Record Status Validated (UNII)
Record Version