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Details

Stereochemistry ACHIRAL
Molecular Formula C6H6AsCl2NO.ClH
Molecular Weight 290.406
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DICHLOROPHENARSINE HYDROCHLORIDE

SMILES

Cl.NC1=C(O)C=CC(=C1)[As](Cl)Cl

InChI

InChIKey=LOYXLMNYVHOJJJ-UHFFFAOYSA-N
InChI=1S/C6H6AsCl2NO.ClH/c8-7(9)4-1-2-6(11)5(10)3-4;/h1-3,11H,10H2;1H

HIDE SMILES / InChI

Molecular Formula C6H6AsCl2NO
Molecular Weight 253.946
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Dichlorophenarsine is a potent anti-syphilitic drug, which exhibits a rapid effect on the serological reactions of the blood in early syphilis. Dichlorophenarsine was more rapid than thiacetarsamide sodium in its action against the canine heartworms infections. Dichlorophenarsine was used for the treatment of canine filariasis - emesia, nausea, and shock occurred several to 30 minutes after injection. Ascorbic acid and hesperidin methyl chalcone when used as a combined therapy afforded a definite protection in mice against the toxic effect of a single dose of intravenously administered dichlorophenarsine hydrochloride.

Approval Year

Patents

Sample Use Guides

In Vivo Use Guide
Sources: DOI: 10.12935/jvma1951.17.603
0.75mg AS/kg daily for two consecutive days.
Route of Administration: Intravenous
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:10:00 GMT 2023
Edited
by admin
on Fri Dec 15 16:10:00 GMT 2023
Record UNII
571850CM3R
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DICHLOROPHENARSINE HYDROCHLORIDE
MI  
Common Name English
DICHLOR-MAPHARSEN
Brand Name English
DICHLOROPHENARSINE HYDROCHLORIDE [MI]
Common Name English
DICHLOROPHENARSINAMMONIUM CHLORIDE, 3-AMINO-4-HYDROXYPHENYLDICHLOROARSINE
Common Name English
DICHLOROPHENARSINE HCL
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C254
Created by admin on Fri Dec 15 16:10:00 GMT 2023 , Edited by admin on Fri Dec 15 16:10:00 GMT 2023
Code System Code Type Description
FDA UNII
571850CM3R
Created by admin on Fri Dec 15 16:10:00 GMT 2023 , Edited by admin on Fri Dec 15 16:10:00 GMT 2023
PRIMARY
CAS
536-29-8
Created by admin on Fri Dec 15 16:10:00 GMT 2023 , Edited by admin on Fri Dec 15 16:10:00 GMT 2023
PRIMARY
NSC
4663
Created by admin on Fri Dec 15 16:10:00 GMT 2023 , Edited by admin on Fri Dec 15 16:10:00 GMT 2023
PRIMARY
PUBCHEM
68301
Created by admin on Fri Dec 15 16:10:00 GMT 2023 , Edited by admin on Fri Dec 15 16:10:00 GMT 2023
PRIMARY
MERCK INDEX
m689
Created by admin on Fri Dec 15 16:10:00 GMT 2023 , Edited by admin on Fri Dec 15 16:10:00 GMT 2023
PRIMARY Merck Index
NCI_THESAURUS
C75248
Created by admin on Fri Dec 15 16:10:00 GMT 2023 , Edited by admin on Fri Dec 15 16:10:00 GMT 2023
PRIMARY
EPA CompTox
DTXSID80201816
Created by admin on Fri Dec 15 16:10:00 GMT 2023 , Edited by admin on Fri Dec 15 16:10:00 GMT 2023
PRIMARY
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ACTIVE MOIETY