Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C20H31N5O3S |
| Molecular Weight | 421.557 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN1N=C(CS(C)(=O)=O)N=C1NCCCOC2=CC=CC(CN3CCCCC3)=C2
InChI
InChIKey=JEYKZWRXDALMNG-UHFFFAOYSA-N
InChI=1S/C20H31N5O3S/c1-24-20(22-19(23-24)16-29(2,26)27)21-10-7-13-28-18-9-6-8-17(14-18)15-25-11-4-3-5-12-25/h6,8-9,14H,3-5,7,10-13,15-16H2,1-2H3,(H,21,22,23)
| Molecular Formula | C20H31N5O3S |
| Molecular Weight | 421.557 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Sufotidine is a triazolamine derivative patented by Glaxo Group Ltd. as long-acting histamine H2-blocker useful for the treatment of peptic ulceration and oesophagitis. In phase II clinical treatment with sufotidine decreases median integrated 24-hour intragastric acidity by 95% compared with placebo. Twice daily sufotidine maintained the pH above 3 throughout the 24 h. Unfortunately, no further development report has been published and it seems, that Sufotidine development currently discontinued.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:36:57 UTC 2023
by
admin
on
Fri Dec 15 15:36:57 UTC 2023
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| Record UNII |
56B0591Y76
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
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NCI_THESAURUS |
C29702
Created by
admin on Fri Dec 15 15:36:57 UTC 2023 , Edited by admin on Fri Dec 15 15:36:57 UTC 2023
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| Code System | Code | Type | Description | ||
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80343-63-1
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71763
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CHEMBL2105496
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SUB10673MIG
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100000083235
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C73217
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DTXSID50230254
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5852
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Y-17
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C062101
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56B0591Y76
Created by
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Sufotidine
Created by
admin on Fri Dec 15 15:36:57 UTC 2023 , Edited by admin on Fri Dec 15 15:36:57 UTC 2023
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
