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Details

Stereochemistry RACEMIC
Molecular Formula C20H24N2S2
Molecular Weight 356.548
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of METITEPINE

SMILES

CSC1=CC2=C(SC3=C(CC2N4CCN(C)CC4)C=CC=C3)C=C1

InChI

InChIKey=RLJFTICUTYVZDG-UHFFFAOYSA-N
InChI=1S/C20H24N2S2/c1-21-9-11-22(12-10-21)18-13-15-5-3-4-6-19(15)24-20-8-7-16(23-2)14-17(18)20/h3-8,14,18H,9-13H2,1-2H3

HIDE SMILES / InChI

Molecular Formula C20H24N2S2
Molecular Weight 356.548
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

Metitepine, a psychotropic agent was developed as a non-selective antagonist of serotonin, dopamine, and adrenergic receptors. Metitepine has never been marketed.

Approval Year

Targets

Primary TargetPharmacologyConditionPotency
56.0 nM [IC50]
8.68 null [pKi]
8.35 null [pKi]
71.0 nM [IC50]
4.7 nM [IC50]
1.5 nM [IC50]
2.0 nM [Ki]
0.4 nM [Ki]

PubMed

Substance Class Chemical
Record UNII
55D94103HL
Record Status Validated (UNII)
Record Version