LORAPRIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C14H22ClN3O3S
Molecular Weight	347.861
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCN1CCCC1CNS(=O)(=O)C2=C(OC)C=C(N)C(Cl)=C2

InChI

InChIKey=YSWVLPFCGJOQQA-UHFFFAOYSA-N

InChI=1S/C14H22ClN3O3S/c1-3-18-6-4-5-10(18)9-17-22(19,20)14-7-11(15)12(16)8-13(14)21-2/h7-8,10,17H,3-6,9,16H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C14H22ClN3O3S
Molecular Weight	347.861
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4087183 | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 741, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ | Milne, G.W.A. (2018) Drugs: Synonyms and Properties, retrieved from: https://books.google.ru/books?id=xUlaDwAAQBAJ

Lorapride is a centrally acting sulfonamide. It has pharmacodynamic properties that are mainly related to ulcer treatment. On the basis of its psychopharmacologic profile, it has no neuroleptic potential, but it does exhibit some psychostimulating components. After oral administration, absorption of lorapride was rapid. The rate of absorption was first order for solution and zero order for capsule.

Approval Year

PubMed

Title	Date	PubMed
Quantitative thin-layer and high-performance liquid chromatographic determination of lorapride in biological fluids and a pharmacokinetic study in humans.	1985-11	4087183

Patents

Sample Use Guides

In Vivo Use Guide

Single dose - 100 mg

Route of Administration: Other

Substance Class	Chemical Created by `admin` on `Wed Apr 02 08:35:27 GMT 2025` Edited by `admin` on `Wed Apr 02 08:35:27 GMT 2025`
Record UNII	549TIC7B4R
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

lorapride [INN]

Preferred Name

English

LORAPRIDE

Official Name

English

5-CHLORO-N1-((1-ETHYL-2-PYRROLIDINYL)METHYL)-2-METHOXYSULFANILAMIDE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29701