U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry RACEMIC
Molecular Formula C18H16ClFN2O3
Molecular Weight 362.783
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PROFLAZEPAM

SMILES

OCC(O)CN1C2=CC=C(Cl)C=C2C(=NCC1=O)C3=CC=CC=C3F

InChI

InChIKey=RCDQRWWSKKYAJG-UHFFFAOYSA-N
InChI=1S/C18H16ClFN2O3/c19-11-5-6-16-14(7-11)18(13-3-1-2-4-15(13)20)21-8-17(25)22(16)9-12(24)10-23/h1-7,12,23-24H,8-10H2

HIDE SMILES / InChI

Molecular Formula C18H16ClFN2O3
Molecular Weight 362.783
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

Proflazepam is benzodiazepine derivative patented by Hoffmann-La Roche, F., und Co., A.-G. as anticonvulsant and muscle relaxant. In preclinical studies, Proflazepam shows activity in pentetrazole test and in the rotating rod test.

Originator

Approval Year

PubMed

Substance Class Chemical
Record UNII
545MN0F125
Record Status Validated (UNII)
Record Version