PROFLAZEPAM

Details

Stereochemistry	RACEMIC
Molecular Formula	C18H16ClFN2O3
Molecular Weight	362.783
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OCC(O)CN1C2=CC=C(Cl)C=C2C(=NCC1=O)C3=CC=CC=C3F

InChI

InChIKey=RCDQRWWSKKYAJG-UHFFFAOYSA-N

InChI=1S/C18H16ClFN2O3/c19-11-5-6-16-14(7-11)18(13-3-1-2-4-15(13)20)21-8-17(25)22(16)9-12(24)10-23/h1-7,12,23-24H,8-10H2

HIDE SMILES / InChI

Molecular Formula	C18H16ClFN2O3
Molecular Weight	362.783
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6686445 | https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=19740411&CC=DE&NR=2347455A1&KC=A1

Proflazepam is benzodiazepine derivative patented by Hoffmann-La Roche, F., und Co., A.-G. as anticonvulsant and muscle relaxant. In preclinical studies, Proflazepam shows activity in pentetrazole test and in the rotating rod test.

Originator

Approval Year

PubMed

Title	Date	PubMed

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:24:43 GMT 2023` Edited by `admin` on `Fri Dec 15 17:24:43 GMT 2023`
Record UNII	545MN0F125
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PROFLAZEPAM

Official Name

English

proflazepam [INN]

Common Name

English

2H-1,4-BENZODIAZEPIN-2-ONE, 7-CHLORO-1-(2,3-DIHYDROXYPROPYL)-5-(2-FLUOROPHENYL)-1,3-DIHYDRO-

Systematic Name

English

(±)-2H-1,4-BENZODIAZEPIN-2-ONE, 7-CHLORO-1-(2,3-DIHYDROXYPROPYL)-5-(2-FLUOROPHENYL)-1,3-DIHYDRO-

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1012