FENCLORAC

Details

Stereochemistry	RACEMIC
Molecular Formula	C14H16Cl2O2
Molecular Weight	287.182
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)C(Cl)C1=CC(Cl)=C(C=C1)C2CCCCC2

InChI

InChIKey=GXEUNRBWEAIPCN-UHFFFAOYSA-N

InChI=1S/C14H16Cl2O2/c15-12-8-10(13(16)14(17)18)6-7-11(12)9-4-2-1-3-5-9/h6-9,13H,1-5H2,(H,17,18)

HIDE SMILES / InChI

Molecular Formula	C14H16Cl2O2
Molecular Weight	287.182
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1008019 | https://www.ncbi.nlm.nih.gov/pubmed/18151 | https://www.ncbi.nlm.nih.gov/pubmed/409117

Fenclorac is a potent nonsteroidal anti-inflammatory agent with significant analgesic and antipyretic activity. It inhibits prostaglandin synthesis both in vitro and in vivo.

Approval Year

PubMed

Title	Date	PubMed
The antiphlogistic, antinociceptive and antipyretic properties of fenclorac.	1976 Nov	1008019
Inhibition of the diarrheal and cardiac actions of arachidonic acid by fenclorac, a new anti-inflammatory agent.	1976 Oct 15	994722
The inhibition of prostaglandin synthetase in vivo by nonsteroidal anti-inflammatory agents.	1977 Jul	409117
Studies on the in vitro inhibition of prostaglandin synthetase by fenclorac (alpha, m-dichloro-p-cyclohexylphenylacetic acid) and indomethacin.	1977 Jun 1	18151

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:22:45 UTC 2023` Edited by `admin` on `Sat Dec 16 16:22:45 UTC 2023`
Record UNII	5458S22S8I
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FENCLORAC

Official Name

English

FENCLORAC [USAN]

Common Name

English

fenclorac [INN]

Common Name

English

Chloro(3-chloro-4-cyclohexylphenyl)acetic acid

Systematic Name

English

WHR-539

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C1323