AP-2238

COC1=CC2=C(C=C1OC)C=C(C(=O)O2)C3=CC=C(CN(C)CC4=CC=CC=C4)C=C3

InChIKey=KXMCSAUVAHKCOR-UHFFFAOYSA-N

InChI=1S/C26H25NO4/c1-27(16-18-7-5-4-6-8-18)17-19-9-11-20(12-10-19)22-13-21-14-24(29-2)25(30-3)15-23(21)31-26(22)28/h4-15H,16-17H2,1-3H3

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Extensive SAR and computational studies of 3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) derivatives.	2007-08-23	17655212
3-(4-[[Benzyl(methyl)amino]methyl]phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) inhibits both acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation: a dual function lead for Alzheimer's disease therapy.	2003-06-05	12773032

Substance Class	Chemical Created by `admin` on `Mon Mar 31 23:00:26 GMT 2025` Edited by `admin` on `Mon Mar 31 23:00:26 GMT 2025`
Record UNII	545225E0BC
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

2H-1-BENZOPYRAN-2-ONE, 6,7-DIMETHOXY-3-(4-((METHYL(PHENYLMETHYL)AMINO)METHYL)PHENYL)-

Preferred Name

English

AP-2238

Common Name

English

Code System Code Type Description

PUBCHEM

9844749

Created by admin on Mon Mar 31 23:00:26 GMT 2025 , Edited by admin on Mon Mar 31 23:00:26 GMT 2025

PRIMARY

CAS

553681-56-4

Created by admin on Mon Mar 31 23:00:26 GMT 2025 , Edited by admin on Mon Mar 31 23:00:26 GMT 2025

PRIMARY

FDA UNII

545225E0BC

Created by admin on Mon Mar 31 23:00:26 GMT 2025 , Edited by admin on Mon Mar 31 23:00:26 GMT 2025

PRIMARY

Related Record Type Details

545225E0BC

AP-2238

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