JWH-146

CCCCCCCN1C=C(C=C1C2=CC=CC=C2)C(=O)C3=C4C=CC=CC4=CC=C3

InChIKey=JDBFNFBWXVCTSA-UHFFFAOYSA-N

InChI=1S/C28H29NO/c1-2-3-4-5-11-19-29-21-24(20-27(29)23-14-7-6-8-15-23)28(30)26-18-12-16-22-13-9-10-17-25(22)26/h6-10,12-18,20-21H,2-5,11,19H2,1H3

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
Cannabinoid CB1 receptor 85 Target ID: CHEMBL3571 Sources: https://www.ncbi.nlm.nih.gov/pubmed/16889960	Agonist 2752		21.0 nM [Ki]
Cannabinoid CB2 receptor 71 Target ID: CHEMBL253 Sources: https://www.ncbi.nlm.nih.gov/pubmed/16889960	Agonist 2752		62.0 nM [Ki]

PubMed

Title	Date	PubMed
1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: new high affinity ligands for the cannabinoid CB1 and CB2 receptors.	2006-10-15	16889960

Substance Class	Chemical Created by `admin` on `Wed Apr 02 05:47:44 GMT 2025` Edited by `admin` on `Wed Apr 02 05:47:44 GMT 2025`
Record UNII	5446SVK6LH
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

(1-HEPTYL-5-PHENYL-PYRROL-3-YL)-NAPHTHALEN-1-YL-METHANONE

Preferred Name

English

JWH-146

Code

English

METHANONE, (1-HEPTYL-5-PHENYL-1H-PYRROL-3-YL)-1-NAPHTHALENYL-

Systematic Name

English

Code System Code Type Description

WIKIPEDIA

JWH-146